ARL4C

Description		ARF like GTPase 4C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Plasma Membrane Membrane Filopodium Cell Projection
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Alpha-tubulin Binding
	Biological Process	Intracellular Protein Transport Endocytic Recycling
Pathways		NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases
GWAS		Blood pressure measurement (high sodium and potassium intervention) ( 24165912) Central corneal thickness ( 29760442) Cognitive decline (age-related) ( 28078323) Initial pursuit acceleration in psychotic disorders ( 29064472) Pancreatic cancer ( 20686608) Systolic blood pressure x educational attainment (some college) interaction (2df) ( 32372009) Triglyceride levels ( 30108155)
Novel Interacting Genes		1 novel interacting genes: GIGYF2
Interacting Genes		2 interacting genes: APP UBQLN4
Entrez ID		10123
HPRD ID		11988
Ensembl ID		ENSG00000188042
Uniprot IDs		P56559
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Adult Locomotory Behavior Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Adult Behavior Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Protein-containing Complex Lipoprotein Particle Perikaryon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Locomotory Behavior Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of Autophagosome Maturation Nuclear Proteasome Complex Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Metabolic Process Cellular Response To Norepinephrine Stimulus Endoplasmic Reticulum Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Cytosolic Proteasome Complex Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Developmental Growth Regulation Of Proteolysis Regulation Of Protein Catabolic Process Heparan Sulfate Binding Signaling Receptor Activator Activity Proximal Dendrite Peptidase Activator Activity Cellular Response To Manganese Ion
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