CDH13

Gene Name		cadherin 13
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Plasma Membrane Caveola Focal Adhesion External Side Of Plasma Membrane Anchored Component Of Membrane Neuron Projection Extracellular Vesicular Exosome
	Molecular Function	Calcium Ion Binding Low-density Lipoprotein Particle Binding Protein Homodimerization Activity Cadherin Binding Adiponectin Binding Lipoprotein Particle Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Cell-matrix Adhesion Sprouting Angiogenesis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Cell Adhesion Rho Protein Signal Transduction Negative Regulation Of Cell Proliferation Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Rac Protein Signal Transduction Lamellipodium Assembly Regulation Of Endocytosis Positive Regulation Of Cell Migration Cell Junction Assembly Adherens Junction Organization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Endothelial Cell Migration Keratinocyte Proliferation Cell-cell Junction Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Positive Chemotaxis Localization Within Membrane Low-density Lipoprotein Particle Mediated Signaling
Pathways		Cell junction organization Cell-cell junction organization Adherens junctions interactions
Drugs
Diseases
GWAS		Adiponectin levels ( 20876611 22479202 22065538 20887962 21771975) Attention deficit hyperactivity disorder ( 18839057) Blood pressure ( 17903302) D-dimer levels ( 21502573) Depression (quantitative trait) ( 20800221) Height ( 20189936) Hypertension ( 19304780) Response to amphetamines ( 22952603) Response to antipsychotic treatment ( 20195266) Response to fenofibrate (adiponectin levels) ( 23149075) Schizophrenia ( 23358160)
Protein-protein Interactions		2 interactors: ADIPOQ MAPK6
Entrez ID		1012
HPRD ID		03219
Ensembl ID		ENSG00000140945
Uniprot IDs		B7Z3H7 B7Z590 B7Z9B1 P55290
PDB IDs		2V37
Enriched GO Terms of Interacting Partners?		Response To Linoleic Acid Positive Regulation Of Renal Albumin Absorption Detection Of Oxidative Stress Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Metanephric Glomerular Visceral Epithelial Cell Development Negative Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Positive Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Metanephric Glomerulus Development Positive Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of CAMP-dependent Protein Kinase Activity Positive Regulation Of Protein Kinase A Signaling Negative Regulation Of Receptor Biosynthetic Process Negative Regulation Of Heterotypic Cell-cell Adhesion Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Receptor Binding Negative Regulation Of Granulocyte Differentiation Adiponectin-activated Signaling Pathway Positive Regulation Of Glomerulus Development Positive Regulation Of Myeloid Cell Apoptotic Process Regulation Of Glycogen (starch) Synthase Activity Negative Regulation Of Macrophage Differentiation Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Protein Heterotrimerization Negative Regulation Of Phagocytosis Negative Regulation Of Protein Autophosphorylation Negative Regulation Of Gluconeogenesis Regulation Of CAMP-dependent Protein Kinase Activity Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Protein Kinase A Signaling Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Receptor Biosynthetic Process Negative Regulation Of Smooth Muscle Cell Migration Cellular Response To Epinephrine Stimulus Response To Sucrose Positive Regulation Of Cholesterol Efflux Response To Epinephrine Positive Regulation Of Cholesterol Transport Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Regulation Of Cholesterol Efflux Negative Regulation Of DNA Biosynthetic Process Low-density Lipoprotein Particle Clearance Cellular Response To Catecholamine Stimulus Regulation Of Protein Autophosphorylation Positive Regulation Of Interleukin-8 Production Positive Regulation Of Fatty Acid Metabolic Process Protein Trimerization Plasma Lipoprotein Particle Clearance
Tagcloud ?		almost alterations conclude cutaneous dapk1 elucidate epigenetic exclusively exposed finally hypermethylation hypomethylation lesional methylation neither normal perilesional protected repetitive represent samples scc sequence sequences skin squamous sun tissues trend