CDH8

Description		cadherin 8
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Adherens Junction Membrane Catenin Complex Synaptic Cleft Axon Terminus Synaptic Membrane Glutamatergic Synapse
	Molecular Function	Calcium Ion Binding Beta-catenin Binding Identical Protein Binding Cadherin Binding Metal Ion Binding
	Biological Process	Cell Morphogenesis Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Chemical Synaptic Transmission Response To Cold Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration Adherens Junction Organization Synaptic Transmission, Glutamatergic Cell-cell Adhesion Mediated By Cadherin Regulation Of Synapse Organization Cell-cell Adhesion
Pathways		Adherens junctions interactions CDH11 homotypic and heterotypic interactions
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Aspartate aminotransferase levels ( 33547301) Automobile speeding propensity ( 30643258) Bitter alcoholic beverage consumption ( 31046077) Caffeine consumption from tea ( 33287642) Cerebrospinal T-tau levels ( 26252872) Clostridioides difficle infection ( 33841421) Cystic fibrosis severity ( 21602797) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) High density lipoprotein cholesterol levels ( 33339817) Lung cancer in never smokers ( 28604730) Mild to moderate chronic kidney disease ( 31178898) Non-small cell lung cancer ( 23144319) Phospholipid levels (plasma) ( 22359512) Response to antidepressants and depression ( 27622933) Rotator cuff injury ( 29228018) Uterine fibroid number (single vs multiple) ( 30196971) White coat effect (clinic diastolic blood pressure minus ambulatory diastolic blood pressure) ( 31044621)
Interacting Genes		1 interacting genes: CTNNB1
Entrez ID		1006
HPRD ID		04306
Ensembl ID		ENSG00000150394
Uniprot IDs		J3QKW5 J3QLE6 P55286
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Mesenchymal Stem Cell Differentiation Oviduct Development Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Beta-catenin-ICAT Complex Negative Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Acinar Cell Differentiation Positive Regulation Of Proteoglycan Biosynthetic Process Fungiform Papilla Formation Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Beta-catenin-TCF7L2 Complex Glial Cell Fate Determination Astrocyte-dopaminergic Neuron Signaling Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Metanephros Morphogenesis Trachea Morphogenesis Regulation Of Mitotic Cell Cycle, Embryonic Renal Inner Medulla Development Scrib-APC-beta-catenin Complex Regulation Of Centriole-centriole Cohesion Renal Outer Medulla Development Renal Vesicle Formation Embryonic Skeletal Limb Joint Morphogenesis Glial Cell-neuron Signaling Lung Induction Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Catenin-TCF7L2 Complex Regulation Of Timing Of Anagen Cellular Response To Indole-3-methanol Mesenchymal Cell Proliferation Involved In Lung Development Central Nervous System Vasculogenesis Cranial Ganglion Development Regulation Of Centromeric Sister Chromatid Cohesion Hair Follicle Placode Formation Dorsal Root Ganglion Development Establishment Of Blood-retinal Barrier Response To Indole-3-methanol Regulation Of Branching Involved In Lung Morphogenesis Positive Regulation Of Blood Vessel Branching Endodermal Cell Fate Commitment Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Limb Joint Morphogenesis Detection Of Muscle Stretch Regulation Of Secondary Heart Field Cardioblast Proliferation Positive Regulation Of Odontoblast Differentiation
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