FARSB

Description		phenylalanyl-tRNA synthetase subunit beta
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GO Annotations	Cellular Component	Cytoplasm Cytosol Phenylalanine-tRNA Ligase Complex Membrane
	Molecular Function	Nucleotide Binding Magnesium Ion Binding RNA Binding Aminoacyl-tRNA Ligase Activity Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding Ligase Activity Metal Ion Binding
	Biological Process	Translation Phenylalanyl-tRNA Aminoacylation Protein Heterotetramerization
Pathways		Cytosolic tRNA aminoacylation
Drugs		Phenylalanine
Diseases
GWAS		Chin dimples ( 27182965) Metabolite levels ( 23823483) Schizophrenia (inflammation and infection response interaction) ( 25781172)
Interacting Genes		5 interacting genes: CEBPA MSRA PTEN SF3B4 SUMO2
Entrez ID		10056
HPRD ID		09947
Ensembl ID		ENSG00000116120
Uniprot IDs		Q9NSD9
PDB IDs		3L4G
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Regulation Of Proteolysis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding L-methionine:thioredoxin-disulfide S-oxidoreductase Activity Peptide-methionine (S)-S-oxide Reductase Activity L-methionine-(S)-S-oxide Reductase Activity Negative Regulation Of Synaptic Vesicle Clustering Positive Regulation Of Catabolic Process Response To Vitamin B2 C/EBP Complex Positive Regulation Of Proteasomal Protein Catabolic Process Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity PML Body Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleoplasm Regulation Of Osteoblast Differentiation CHOP-C/EBP Complex Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Positive Regulation Of Protein Metabolic Process Developmental Maturation Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process White Fat Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol Phosphate Phosphatase Activity Macromolecule Metabolic Process Regulation Of Synaptic Vesicle Clustering Splicing Factor Binding Response To Phenylpropanoid Protein Repair Negative Regulation Of Peptidyl-serine Phosphorylation Postsynaptic Density Assembly Learning Or Memory Negative Regulation Of Cell Development Fat Cell Proliferation Neuron-neuron Synaptic Transmission Negative Regulation Of Cell Size Anaphase-promoting Complex Binding
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