ZBTB5 and JADE2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		ZBTB5	JADE2
Description		zinc finger and BTB domain containing 5	jade family PHD finger 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Histone Acetyltransferase Complex Nucleoplasm Extracellular Exosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Zinc Ion Binding Transferase Activity Histone H3K14 Acetyltransferase Activity Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Metal Ion Binding Histone H4K16 Acetyltransferase Activity Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Regulation Of Cell Growth Regulation Of DNA Replication Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination Regulation Of Cell Cycle Regulation Of DNA Biosynthetic Process
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Daytime nap ( 33568662)	Adult body size ( 32376654) Age at first birth ( 34211149 27798627) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Coffee consumption ( 31046077) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hand grip strength ( 29691431) Household income (MTAG) ( 31844048) Mental health study participation (completed survey) ( 31263887) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Platelet distribution width ( 27863252) Smoking cessation ( 33082346) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 28869590) White blood cell count ( 32888494)
Interacting Genes		17 interacting genes: BAG4 BCOR CCDC85B DCX EP300 JADE2 METTL5 NCOR1 NCOR2 PPARG PTPN5 RSPH1 SP1 ST3GAL3 SWAP70 TP53 ZBTB7B	27 interacting genes: C5orf15 CBX8 CDCA7L CSNK2A1 DDX46 FBXO7 FSTL4 GAS2L2 GORASP2 H3-4 ING4 IRAK1 KLK2 PACSIN1 RAPGEF6 SAR1B SASH1 SH2B2 SMAD5-AS1 TCF7 TTC3 UQCRQ ZBTB3 ZBTB5 ZCCHC10 ZNF417 ZNF496
Entrez ID		9925	23338
HPRD ID		08829	15124
Ensembl ID		ENSG00000168795	ENSG00000043143
Uniprot IDs		O15062 Q5T942	A0A087X085 A0A0C4DFT8 B3KPL2 B4DFY8 G3XAA4 Q9NQC1
PDB IDs		9B9R
Enriched GO Terms of Interacting Partners?		Histone Deacetylase Binding Rhythmic Process Transcription Repressor Complex Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of MiRNA Transcription Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Cis-regulatory Region Binding Transcription Coregulator Binding Nuclear Receptor Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Carbohydrate Catabolic Process STAT Family Protein Binding Regulation Of RNA Metabolic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Purine Nucleotide Metabolic Process Nuclear Retinoid X Receptor Binding Negative Regulation Of Androgen Receptor Signaling Pathway Host-mediated Activation Of Viral Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Mitochondrion Organization Negative Regulation Of Small Molecule Metabolic Process Circadian Behavior Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Rhythmic Behavior Mononuclear Cell Differentiation Histone Acetyltransferase Complex Regulation Of Small Molecule Metabolic Process Regulation Of Ketone Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Circadian Rhythm Regulation Of Intracellular Signal Transduction Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Fat Cell Differentiation Regulation Of T-helper 17 Cell Differentiation Host-mediated Perturbation Of Viral Transcription Regulation Of Primary Metabolic Process Chromatin Positive Regulation Of Apoptotic Signaling Pathway DNA Binding T Cell Lineage Commitment Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Leukocyte Differentiation
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