FAM20B and SLC7A14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM20B	SLC7A14
Description		FAM20B glycosaminoglycan xylosylkinase	solute carrier family 7 member 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Cytoplasm Golgi Apparatus Membrane	Nucleoplasm Lysosome Lysosomal Membrane Cytosol Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Kinase Activity Transferase Activity Phosphotransferase Activity, Alcohol Group As Acceptor Metal Ion Binding	Protein Binding Amino Acid Transmembrane Transporter Activity Gamma-aminobutyric Acid Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Proteoglycan Biosynthetic Process	Amino Acid Transmembrane Transport Amino Acid Transport Gamma-aminobutyric Acid Import Transmembrane Transport
Pathways		Glycosaminoglycan-protein linkage region biosynthesis
Drugs
Diseases
GWAS		Systemic lupus erythematosus ( 32771030)	Obesity (extreme) ( 30677029) Spontaneous preterm birth without premature rupture of membranes ( 31194736)
Interacting Genes		9 interacting genes: FAM209A FFAR2 GOLPH3 GOLPH3L GPR152 KCNJ6 SLC7A14 TIMMDC1 TMEM80	47 interacting genes: ACSL5 ADGRE2 AGTRAP AIG1 APOL3 BET1 BNIP1 BNIP2 C1GALT1 CBLIF CCDC167 CCL4L2 CD53 CMTM5 DCBLD2 DERL1 EOGT ERMP1 FAM209A FAM20B FATE1 FCER1G FKBP7 IL10RA LINC00839 LTC4S MFF MGLL MMGT1 NINJ2 NSG1 PLPP6 PRB1 SCARF1 SCD SMCO4 TECR TMEM128 TMEM31 TRARG1 TREX1 UBIAD1 VAMP2 VKORC1 YIPF4 YIPF6 ZFPL1
Entrez ID		9917	57709
HPRD ID		13297	17222
Ensembl ID		ENSG00000116199	ENSG00000013293
Uniprot IDs		O75063	Q8TBB6
PDB IDs
Enriched GO Terms of Interacting Partners?		Golgi Vesicle Budding Cargo Adaptor Activity Protein Targeting To Golgi Apparatus Golgi Cisterna Positive Regulation Of Protein Secretion Phosphatidylinositol-4-phosphate Binding Golgi To Plasma Membrane Protein Transport Vesicle Budding From Membrane Regulation Of Protein Secretion Positive Regulation Of Protein Transport Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Positive Regulation Of Secretion By Cell Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Golgi Cisterna Membrane Golgi To Plasma Membrane Transport Lipid Binding Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Asymmetric Golgi Ribbon Formation Positive Regulation Of Protein Localization Regulation Of Protein Transport Post-Golgi Vesicle-mediated Transport Cell Adhesion Molecule Production Cellular Response To Rapamycin Golgi Organization Regulation Of Establishment Of Protein Localization G-protein Activated Inward Rectifier Potassium Channel Activity Vesicle-mediated Transport To The Plasma Membrane Protein Retention In Golgi Apparatus Regulation Of Secretion By Cell Gamma-aminobutyric Acid Import Gamma-aminobutyric Acid Transmembrane Transporter Activity Response To Rapamycin Regulation Of Secretion Trans-Golgi Network Leukocyte Chemotaxis Involved In Inflammatory Response Protein Localization To Plasma Membrane Protein Targeting Establishment Of Protein Localization To Membrane Golgi Ribbon Formation Cellular Response To Ether Protein Localization To Cell Periphery Regulation Of Transport	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organelle Membrane Fusion Organelle Fusion Vesicle-mediated Transport Membrane Fusion SNAP Receptor Activity Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Vesicle Fusion Vesicle Fusion With Golgi Apparatus Cobalt Ion Transport SNARE Complex Nuclear Envelope Fatty Acid Biosynthetic Process Intestinal Epithelial Cell Development Response To Oxygen-glucose Deprivation Establishment Of Protein Localization To Plasma Membrane Vitamin K Metabolic Process Endosome To Plasma Membrane Protein Transport Endomembrane System Columnar/cuboidal Epithelial Cell Development Golgi Vesicle Transport
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