TRANK1 and LRRFIP2

		TRANK1	LRRFIP2
Description		tetratricopeptide repeat and ankyrin repeat containing 1	LRR binding FLII interacting protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component
	Molecular Function		Protein Binding LRR Domain Binding
	Biological Process		Regulation Of DNA-templated Transcription Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 22182935 34002096 24618891 33263727 27329760 28072414 28115744 31043756) Bipolar disorder with mood-incongruent psychosis ( 23092984) Bipolar I disorder ( 31043756) Chronotype ( 30696823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Iris color (L* coordinate) ( 29109912) Kleine-Levin syndrome ( 33737391) Mean platelet volume ( 32888494) Morning person ( 30696823) Platelet distribution width ( 27863252) Pulse pressure ( 30224653) Schizophrenia ( 29483656 25056061 28991256 30285260) Schizophrenia or bipolar disorder ( 24280982) Subjective response to lithium treatment ( 26503763) Triglycerides ( 30275531)	Autism spectrum disorder or schizophrenia ( 28540026) Femur bone mineral density x serum urate levels interaction ( 34046847) Subjective response to lithium treatment ( 26503763)
Interacting Genes		5 interacting genes: ANO10 APRG1 DCLK3 LRRFIP2 XIRP1	5 interacting genes: ATPAF2 DNAJC19 FLII OGT TRANK1
Entrez ID		9881	9209
HPRD ID		19247	10061
Ensembl ID		ENSG00000168016	ENSG00000093167
Uniprot IDs		A0A2R8YEM9 O15050	A0A1S5UZ17 Q9Y608
PDB IDs
Enriched GO Terms of Interacting Partners?		LRR Domain Binding Myoblast Differentiation Involved In Skeletal Muscle Regeneration Satellite Cell Activation Involved In Skeletal Muscle Regeneration Skeletal Muscle Satellite Cell Activation	Negative Regulation Of Protein-containing Complex Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein N-acetylglucosaminyltransferase Complex Non-canonical Inflammasome Complex Assembly Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Mitochondrial Proton-transporting ATP Synthase Complex Assembly Proton-transporting ATP Synthase Complex Assembly Matrix Side Of Mitochondrial Inner Membrane Inner Mitochondrial Membrane Protein Complex PAM Complex, Tim23 Associated Import Motor Regulation Of Cardiolipin Metabolic Process Membraneless Organelle Assembly Regulation Of Transcription By Glucose
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