RB1CC1 and IL24

Number of citations of the paper that reports this interaction (PubMedID 25640309)
0

Data Source:
BioGRID (two hybrid)

		RB1CC1	IL24
Description		RB1 inducible coiled-coil 1	interleukin 24
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GO Annotations	Cellular Component	Phagophore Assembly Site Autophagosome Membrane Nucleus Cytoplasm Lysosome Vacuole Endoplasmic Reticulum Membrane Cytosol Organelle Membrane Nuclear Membrane Phagophore Assembly Site Membrane Atg1/ULK1 Kinase Complex	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Protein Kinase Binding Protein-membrane Adaptor Activity Molecular Adaptor Activity	Cytokine Activity Protein Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Pexophagy Liver Development Autophagy Apoptotic Process Heart Development Negative Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Ribophagy Piecemeal Microautophagy Of The Nucleus Negative Regulation Of Apoptotic Process Innate Immune Response Positive Regulation Of Cell Size Positive Regulation Of JNK Cascade Defense Response To Virus Reticulophagy Glycophagy Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Apoptotic Process Immune Response Signal Transduction Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Migration Cellular Response To Lipopolysaccharide Cellular Response To Interleukin-4
Pathways		Macroautophagy	Interleukin-20 family signaling
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Immunoglobulin light chain (AL) amyloidosis (liver involvement) ( 28679651) Mitochondrial DNA copy number (white blood cells) ( 30704525) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 28552196)	Inflammatory bowel disease ( 23128233)
Interacting Genes		35 interacting genes: ATG12 AZI2 BAP1 BLID CALCOCO2 COP1 EPSTI1 ERRFI1 EXOC1 GABARAP GABARAPL1 GABARAPL2 GLCE GREB1 HBP1 IL13RA2 IL24 ITIH5 LYPD3 MADD MECOM MRC2 NSD3 PSMC3IP PTK2 PTK2B RNF20 SYN1 THRSP UBC UMPS VAPA VHL VPS45 WIF1	28 interacting genes: AKT1 APC ATM BAG4 CASP8 CCR5 CLU DCD ESR2 FBXW7 HMMR HRAS IL20RA KRAS LSP1 NOTCH2 PALB2 PARP1 PIK3CA PTEN RAD51 RARG RB1CC1 RIPK3 S100A6 S100P SMAD4 UBE3A
Entrez ID		9821	11009
HPRD ID		06019	04995
Ensembl ID		ENSG00000023287	ENSG00000162892
Uniprot IDs		Q8TDY2	Q13007
PDB IDs		6DCE 6GMA 7CZG 7CZM 7D0E 7EA2 7EAA 8SOI 8SQZ 8SRM 8W6B 8YFK 8YFL 8YFM 8YFN 9C82 9D34	6DF3 6GG1
Enriched GO Terms of Interacting Partners?		Autophagosome Membrane Autophagosome Cellular Response To Nitrogen Starvation Autophagosome Maturation Phosphatidylethanolamine Binding GABA Receptor Binding Autophagy Of Mitochondrion Macroautophagy Autophagosome Assembly Autophagosome Organization Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Beta-tubulin Binding Signal Complex Assembly Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein-containing Complex Disassembly Mitophagy Glycophagy Epidermal Growth Factor Receptor Signaling Pathway Apoptotic Process Ubiquitin Protein Ligase Binding Autophagy Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Tag Activity Vacuole Organization Regulation Of Autophagosome Maturation Programmed Cell Death Cell Death ERBB Signaling Pathway Protein Localization To Endoplasmic Reticulum Positive Regulation Of Proteolysis Glycogen Catabolic Process Regulation Of Proteolysis Histone H3 Methyltransferase Activity Catabolic Process Polysaccharide Catabolic Process Regulation Of Macrophage Chemotaxis Cellular Response To Fluid Shear Stress Neurotransmitter Receptor Regulator Activity Orotidine-5'-phosphate Decarboxylase Activity Orotate Phosphoribosyltransferase Activity Nucleate Erythrocyte Differentiation Thrombocyte Differentiation Golgi Membrane Phospholipid Binding Heparosan-N-sulfate-glucuronate 5-epimerase Activity Meiotic Joint Molecule Formation DNA Recombinase Auxiliary Factor Complex Recombinase Activator Activity Meiotic Strand Invasion Involved In Reciprocal Meiotic Recombination Histone H3K4 Dimethyltransferase Activity	Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Positive Regulation Of Intracellular Signal Transduction Apoptotic Process Programmed Cell Death Cell Death Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Neuron Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Stress Regulation Of Signal Transduction Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Gland Development Intracellular Signal Transduction Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Protein-containing Complex Binding Negative Regulation Of Programmed Cell Death Animal Organ Development Response To Lipid Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Process Cellular Response To Oxygen-containing Compound Apoptotic Signaling Pathway Positive Regulation Of Cellular Component Biogenesis Identical Protein Binding Response To Gamma Radiation Myelin Maintenance Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Intracellular Signal Transduction Protein-containing Complex Regulation Of Multicellular Organismal Process Regulation Of Apoptotic Signaling Pathway Regulation Of Biological Quality Positive Regulation Of Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Defense Response Cell Surface Receptor Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Response To Radiation
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