CTIF and ATXN7L2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CTIF	ATXN7L2
Description		cap binding complex dependent translation initiation factor	ataxin 7 like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding Translation Activator Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Translation Regulation Of Translational Initiation Positive Regulation Of Translation
Pathways
Drugs
Diseases
GWAS		Automobile speeding propensity ( 30643258) Ceramide levels (C22:0) ( 32489964) Ceramide levels (C24:0) ( 32489964) Height ( 31562340) Hematocrit ( 32888494) Hemoglobin ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Iris heterochromicity ( 30895295) Large HDL particle concentration ( 29084231) Lumbar spine bone mineral density (integral) ( 27476799) Mean diameter of HDL particles ( 29084231) Phospholipid levels in large HDL ( 29084231) Red blood cell count ( 27863252 32888494) Response to carboplatin in ovarian cancer (MTT IC50) ( 27047539) Rheumatoid arthritis ( 30891314) White blood cell count ( 32888494)	Chronic kidney disease ( 20383146) Intelligence (MTAG) ( 29326435) Major depressive disorder ( 20125088)
Interacting Genes		8 interacting genes: ATPAF2 ATXN7L2 DCTN1 EEF1A1 HEXIM2 HOOK3 RECK SPG21	27 interacting genes: BAG3 BANP CBX1 CBX3 CTIF CYSRT1 FSD2 GOLGA6L9 HSF2BP HSPB8 IKZF3 KCTD7 KRT31 LAMB1 MB21D2 MDFI PACSIN3 PPP1R16A PPP2R3A PRDM6 RBPMS SBK3 SH3RF1 SH3RF2 SSC4D USP54 ZNF526
Entrez ID		9811	127002
HPRD ID		11083	12506
Ensembl ID		ENSG00000134030	ENSG00000162650
Uniprot IDs		O43310	A0A804HIT1 A0A804HIX1 A0A804HJY2 Q5T6C5
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Microtubule Anchoring Nuclear Migration Nucleus Localization Response To Epidermal Growth Factor	Identical Protein Binding Positive Regulation Of Aggrephagy Positive Regulation Of Catabolic Process Positive Regulation Of Protein Catabolic Process Cellular Response To Unfolded Protein Histone Methyltransferase Binding
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