SCRN1 and GORASP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SCRN1	GORASP1
Description		secernin 1	golgi reassembly stacking protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Nuclear Membrane Presynapse	Golgi Membrane Golgi Apparatus Cis-Golgi Network Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding Dipeptidase Activity Cysteine-type Exopeptidase Activity	Protein Binding Metal Ion Binding
	Biological Process	Proteolysis Exocytosis Regulation Of Synaptic Vesicle Cycle	Protein N-linked Glycosylation Golgi Organization Protein Transport Negative Regulation Of Dendrite Morphogenesis Establishment Of Protein Localization To Plasma Membrane Golgi Ribbon Formation
Pathways			Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Psoriasis ( 25854761)	Social communication problems ( 24564958)
Interacting Genes		5 interacting genes: GORASP1 HGS NPC2 OGT ZNF25	21 interacting genes: AGPS BSN CASP3 CASP7 CDK1 CLEC3B ENSA GOLGA2 HIPK3 LONRF1 MAPK6 NEFL OXSR1 PLK1 PRKD2 RPS6KA1 SCRN1 TGFA TMED2 TMED3 TRAF4
Entrez ID		9805	64689
HPRD ID		15304	06038
Ensembl ID		ENSG00000136193	ENSG00000114745
Uniprot IDs		A0A090N7T9 Q12765	A0A8Q3SHU6 A0A8Q3WL08 B3KPY8 B4E1H8 Q9BQQ3
PDB IDs			4REY 6G8T 6G8W
Enriched GO Terms of Interacting Partners?		Protein Localization To Lysosome Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Protein Localization To Vacuole Negative Regulation Of Developmental Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Glycoprotein Biosynthetic Process Positive Regulation Of Transcription By Glucose Macroautophagy Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity ESCRT-0 Complex Phagocytic Vesicle Lumen Cholesterol Storage Sterol Binding Regulation Of Isoprenoid Metabolic Process Carbon Catabolite Regulation Of Transcription Glycoprotein Metabolic Process Glycolipid Transport Autophagy Regulation Of Transcription By Glucose Negative Regulation Of Multicellular Organismal Process Golgi Ribbon Formation Negative Regulation Of Dendrite Morphogenesis NSL Complex Regulation Of Lipid Metabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway	Protein Serine Kinase Activity Golgi Organization Protein Phosphorylation Phosphorylation Protein Serine/threonine Kinase Activity Regulation Of Synaptic Vesicle Cycle Protein Kinase Activity Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Kinase Activity Protein Modification Process Cellular Response To Staurosporine COPII-coated ER To Golgi Transport Vesicle Regulation Of Apoptotic Process Golgi Disassembly Regulation Of Programmed Cell Death Centrosome Cycle Hepatocyte Proliferation G2/M Transition Of Mitotic Cell Cycle Protein Metabolic Process Cell Cycle G2/M Phase Transition Potassium Channel Inhibitor Activity Golgi Cisterna Membrane Fibroblast Apoptotic Process Mitotic Nuclear Membrane Disassembly Transferase Activity Intracellular Signal Transduction Nuclear Membrane Disassembly Microtubule Organizing Center Organization Membrane Disassembly COPI-coated Vesicle Membrane Protein Kinase Binding Cytoplasm Protein Poly-ADP-ribosylation Aspartic-type Endopeptidase Activity Neuron Apoptotic Process Peptidyl-threonine Phosphorylation Execution Phase Of Apoptosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Localization To Site Of Double-strand Break Microtubule Cytoskeleton Organization Involved In Mitosis Apoptotic Process Programmed Cell Death Cell Death Mitotic Cell Cycle Phase Transition Mitotic G2 DNA Damage Checkpoint Signaling Phosphate-containing Compound Metabolic Process Cellular Response To Alkaloid ATP Binding Chromosome Condensation Cell Cycle Phase Transition
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