PHYHIP and WDR89

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PHYHIP	WDR89
Description		phytanoyl-CoA 2-hydroxylase interacting protein	WD repeat domain 89
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Protein Binding Protein Tyrosine Kinase Binding
	Biological Process	Intracellular Protein Localization	Ventricular System Development Corpus Callosum Development
Pathways
Drugs
Diseases
GWAS		Hypertriglyceridemia ( 23505323)	Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
Interacting Genes		24 interacting genes: ADGRB1 COPS6 DYRK1A EEF1A1 ERG28 FAM131A HDAC11 HNRNPA1 MAGED4B MED8 METTL18 NDRG1 NDUFV3 NFE2 PHYH PNPLA2 PPIE PRMT5 S100A13 SMARCC2 SUPT5H TTR WDR89 ZZEF1	5 interacting genes: APP PHYHIP POLR2M POLR3F SOCS6
Entrez ID		9796	112840
HPRD ID		16345	12635
Ensembl ID		ENSG00000168490	ENSG00000140006
Uniprot IDs		Q92561	Q96FK6
PDB IDs
Enriched GO Terms of Interacting Partners?			Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway DNA-directed RNA Polymerase Complex Maintenance Of ER Location Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Endoplasmic Reticulum Localization Heparan Sulfate Binding Signaling Receptor Activator Activity Transcription Elongation Factor Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel
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