DZIP3 and HOTAIR

Number of citations of the paper that reports this interaction (PubMedID 24326307)
39

Data Source:
BioGRID (affinity chromatography technology, unspecified method)

		DZIP3	HOTAIR
Description		DAZ interacting zinc finger protein 3	HOX transcript antisense RNA
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Phosphatase Binding Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 27863252)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		54 interacting genes: AKTIP AP1M1 ARHGAP32 ATXN1 BAG4 BIRC2 BIRC3 CARM1 CCND1 CEP63 DAZ1 FBXO17 GRIP1 GTF2H2C_2 HNRNPF HNRNPH1 HNRNPUL1 HOTAIR HOXC8 MIR20A MIR29C NCOR1 PCGF3 PITX1 RAD18 RBM4B RNF38 RUNX1 TNFRSF18 TNS2 TOLLIP TRIM21 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2N UBE2R2 UBE2U UBE2V1 UBE2V2 UBE2W UBE2Z UBR3 ZCCHC10 ZNF24 ZNF765	5 interacting genes: AR ATXN1 DZIP3 ELAVL1 EZH2
Entrez ID		9666	100124700
HPRD ID		10562
Ensembl ID		ENSG00000198919	ENSG00000228630
Uniprot IDs		Q86Y13
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Ubiquitin-protein Transferase Activity Post-translational Protein Modification Proteolysis Involved In Protein Catabolic Process Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Monoubiquitination Macromolecule Catabolic Process Protein Modification Process Protein K63-linked Ubiquitination Proteolysis Regulation Of Protein Polyubiquitination Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Protein Polyubiquitination Protein K11-linked Ubiquitination Transferase Activity Protein Metabolic Process Positive Regulation Of Protein K63-linked Ubiquitination Macromolecule Metabolic Process UBC13-MMS2 Complex Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Post-translational Protein Modification Regulation Of Protein Modification Process Regulation Of Protein Metabolic Process Postreplication Repair Ubiquitin Conjugating Enzyme Complex Ubiquitin Protein Ligase Activity Nucleus Positive Regulation Of Post-translational Protein Modification Proteasomal Protein Catabolic Process Positive Regulation Of Protein Modification Process Regulation Of Metabolic Process Catabolic Process Nucleoplasm Positive Regulation Of Protein Ubiquitination Regulation Of Protein Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process ATP Binding DNA Damage Response Positive Regulation Of Protein Metabolic Process Error-free Postreplication DNA Repair Negative Regulation Of Macromolecule Metabolic Process DNA Repair Regulation Of RNA Metabolic Process	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway LncRNA Binding Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Prostate Induction Negative Regulation Of RNA Metabolic Process Chromatin Binding Male Somatic Sex Determination Positive Regulation Of Autophagosome Size RNA Binding Hepatocyte Homeostasis Regulation Of Gliogenesis Lateral Sprouting Involved In Mammary Gland Duct Morphogenesis Cellular Response To Trichostatin A Negative Regulation Of Macromolecule Biosynthetic Process Male Genitalia Morphogenesis POU Domain Binding Tertiary Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Cell Differentiation Positive Regulation Of Integrin Biosynthetic Process Regulatory NcRNA-mediated Gene Silencing Regulation Of Autophagosome Size Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Histone H3K27 Trimethyltransferase Activity Response To Tetrachloromethane POZ Domain Binding Positive Regulation Of Cell Population Proliferation Androgen Binding Negative Regulation Of Biosynthetic Process LncRNA-mediated Post-transcriptional Gene Silencing Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Prostatic Bud Formation Regulation Of Developmental Process Postsynapse Histone H3K27 Methyltransferase Activity RNA Polymerase II General Transcription Initiation Factor Binding Cellular Response To Testosterone Stimulus Nuclear Transport Nucleocytoplasmic Transport Pronucleus Negative Regulation Of Retinoic Acid Receptor Signaling Pathway Cerebellar Cortex Development Negative Regulation Of Macromolecule Metabolic Process Transcription Cis-regulatory Region Binding Poly(G) Binding Lateral Sprouting From An Epithelium Epithelial Cell Differentiation Involved In Prostate Gland Development Primary MiRNA Binding
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