ATP5MJ and MTCH2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATP5MJ	MTCH2
Description		ATP synthase membrane subunit j	mitochondrial carrier 2
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane Proton-transporting ATP Synthase Complex	Nucleus Mitochondrion Mitochondrial Outer Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding Membrane Insertase Activity
	Biological Process	Proton Motive Force-driven ATP Synthesis	Lactate Metabolic Process Mitochondrial Transport Regulation Of Mitochondrial Fusion Negative Regulation Of Mitochondrial Membrane Potential Hematopoietic Stem Cell Migration Mitochondrial ATP Synthesis Coupled Electron Transport Positive Regulation Of Apoptotic Process Protein Insertion Into Mitochondrial Outer Membrane Negative Regulation Of Glycolytic Process Lipid Homeostasis Hematopoietic Stem Cell Homeostasis Protein Localization To Mitochondrion Cellular Response To Radiation Establishment Of Protein Localization To Mitochondrial Membrane Establishment Of Protein Localization To Mitochondrial Membrane Involved In Mitochondrial Fission Hepatocyte Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Stem Cell Differentiation
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation
Drugs
Diseases
GWAS			Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Bitter beverage consumption ( 31046077) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 20935630 29381148 29273807 28892062 28448500 26961502 19079261 25673413) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 27841878) Fruit consumption ( 32066663) General cognitive ability ( 29844566) Haemorrhoidal disease ( 33888516) Hypertension ( 31879980) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Mood instability ( 31168069) Neuroticism ( 29255261) Pulse pressure ( 27841878) Refractive error ( 32231278) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Sleep duration (short sleep) ( 30846698) Systolic blood pressure ( 27841878) Walking pace ( 33128006)
Interacting Genes		5 interacting genes: APOC1 BAG5 CIDEB MTCH2 PIN1	6 interacting genes: AMBRA1 APOC1 ATP5MJ ESR1 GLP1R XRN1
Entrez ID		9556	23788
HPRD ID		05199	14788
Ensembl ID		ENSG00000156411	ENSG00000109919
Uniprot IDs		P56378	B4DHQ0 E9PIE4 Q9Y6C9
PDB IDs		8H9F 8H9J 8H9M 8H9Q 8H9S 8H9T 8H9U 8H9V 8KHF 8KI3
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Catabolic Process Very-low-density Lipoprotein Particle Assembly Protein-lipid Complex Assembly Plasma Lipoprotein Particle Assembly Regulation Of Triglyceride Metabolic Process Establishment Of Protein Localization To Mitochondrion Negative Regulation Of Phosphatidylcholine Catabolic Process Cis-trans Isomerase Activity Regulation Of Phosphorus Metabolic Process Negative Regulation Of Small Molecule Metabolic Process Negative Regulation Of Protein Catabolic Process Negative Regulation Of Protein Refolding Establishment Of Protein Localization To Mitochondrial Membrane Involved In Mitochondrial Fission Negative Regulation Of Phosphate Metabolic Process Lipid Homeostasis Regulation Of Phosphatidylcholine Catabolic Process Protein Peptidyl-prolyl Isomerization Phosphothreonine Residue Binding Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Regulation Of Intrinsic Apoptotic Signaling Pathway Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Negative Regulation Of Protein Folding Lipid Droplet Fusion Phosphatidylcholine-sterol O-acyltransferase Activator Activity Negative Regulation Of Triglyceride Catabolic Process Phosphoserine Residue Binding Junctional Membrane Complex Regulation Of Cellular Component Organization Regulation Of Primary Metabolic Process Protein Stabilization Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Organelle Organization Hematopoietic Stem Cell Migration Regulation Of Lipid Metabolic Process Lipid Transport Regulation Of Phosphatidylcholine Metabolic Process Chylomicron Regulation Of Small Molecule Metabolic Process Negative Regulation Of Metabolic Process Phospholipid Efflux Protein-containing Complex Assembly Phospholipase Inhibitor Activity Mitogen-activated Protein Kinase Kinase Binding GTPase Activating Protein Binding Ubiquitin Ligase Activator Activity Establishment Of Protein Localization To Organelle Regulation Of Protein Folding	Negative Regulation Of Phosphatidylcholine Catabolic Process Negative Regulation Of Muscle Cell Apoptotic Process Glucagon-like Peptide 1 Receptor Activity Cellular Response To Puromycin Cellular Response To Cycloheximide Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Regulation Of Phosphatidylcholine Catabolic Process Nuclear Estrogen Receptor Activity Regulation Of Branching Involved In Prostate Gland Morphogenesis Positive Regulation Of Cytosolic Calcium Ion Concentration TFIIB-class Transcription Factor Binding Prostate Epithelial Cord Elongation Positive Regulation Of Nitric-oxide Synthase Activity Mammary Gland Branching Involved In Pregnancy Antral Ovarian Follicle Growth Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Response To Psychosocial Stress Glucagon Receptor Activity Response To Cycloheximide 5'-3' RNA Exonuclease Activity Positive Regulation Of Free Ubiquitin Chain Polymerization Phosphatidylcholine-sterol O-acyltransferase Activator Activity Negative Regulation Of Triglyceride Catabolic Process Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Cellular Response To Oxygen-containing Compound Regulation Of Nitric-oxide Synthase Activity Response To Mitochondrial Depolarisation Steroid Metabolic Process Nitric-oxide Synthase Regulator Activity Post-translational Protein Targeting To Membrane, Translocation G-quadruplex RNA Binding Phospholipase Inhibitor Activity G-quadruplex DNA Binding Regulation Of Phosphatidylcholine Metabolic Process Prostate Gland Growth Vagina Development 5'-3' Exonuclease Activity Very-low-density Lipoprotein Particle Assembly Estrogen Response Element Binding Cellular Response To Glucagon Stimulus Nuclear MRNA Surveillance Branching Involved In Prostate Gland Morphogenesis Chylomicron Phospholipid Efflux Branch Elongation Of An Epithelium
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