ATP5MF and CAPNS1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATP5MF	CAPNS1
Description		ATP synthase membrane subunit f	calpain small subunit 1
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Nuclear Membrane Proton-transporting ATP Synthase Complex	Cytoplasm Cytosol Plasma Membrane Membrane Extracellular Exosome Calpain Complex
	Molecular Function	Proton-transporting ATP Synthase Activity, Rotational Mechanism	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Proteolysis Positive Regulation Of Cell Population Proliferation Regulation Of Macroautophagy
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation	Degradation of the extracellular matrix Degradation of the extracellular matrix Formation of the cornified envelope Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
Drugs			PD150606
Diseases
GWAS
Interacting Genes		15 interacting genes: ARL8B CAPNS1 CCDC137 CDC42 CRELD1 FBP1 HAP1 KDM1A LPP NDUFA6 NECTIN2 PRPF4 RPLP1 TIAM1 ZFPL1	21 interacting genes: AGTRAP ARHGEF6 ARR3 ATP5MF CAPN1 CAPN2 CAST CDC42 CDK4 DRG1 F2RL1 GET4 GNB2 IL2RG KCTD7 LRRCC1 PPARGC1A RAB1A STAT3 TERF1 TRAF5
Entrez ID		9551	826
HPRD ID		16520	00240
Ensembl ID		ENSG00000241468	ENSG00000126247
Uniprot IDs		P56134	A0A0C4DGQ5 P04632
PDB IDs		8H9F 8H9J 8H9M 8H9Q 8H9S 8H9T 8H9U 8H9V 8KHF 8KI3	1KFU 1KFX 4PHJ 4PHK 4PHM 4WQ2 4WQ3 5D69 6QLB
Enriched GO Terms of Interacting Partners?		Organelle Localization Wnt Signaling Pathway, Planar Cell Polarity Pathway Cell-cell Junction Focal Adhesion Establishment Of Organelle Localization Microtubule-based Transport Transport Along Microtubule GBD Domain Binding Storage Vacuole Positive Regulation Of Cell Projection Organization Non-canonical Wnt Signaling Pathway Spindle Midzone Cytoskeleton-dependent Intracellular Transport G Protein Activity Cellular Response To CAMP Phosphoric Ester Hydrolase Activity Cellular Response To Raffinose Fructose 1,6-bisphosphate 1-phosphatase Activity Natural Killer Cell Mediated Immunity Natural Killer Cell Mediated Cytotoxicity Cell-cell Contact Zone Coreceptor-mediated Virion Attachment To Host Cell Cellular Anatomical Entity Morphogenesis Susceptibility To T Cell Mediated Cytotoxicity Sperm Mitochondrion Organization Mitochondrion Localization Positive Regulation Of Neurogenesis Positive Regulation Of Nervous System Development Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Neurotrophin Production Axon Cytoplasm Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Axonal Transport Anterograde Axonal Transport Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Antigen Processing And Presentation Following Phagocytosis Antigen Processing And Presentation Of Polysaccharide Antigen Via MHC Class II Endosome To Lysosome Transport Of Low-density Lipoprotein Particle Viral Exocytosis Regulation Of Plasma Membrane Bounded Cell Projection Organization Endothelin Receptor Signaling Pathway Involved In Heart Process Organelle Transport Along Microtubule Regulation Of Cell Projection Organization Cellular Hypotonic Salinity Response Fusion Of Virus Membrane With Host Plasma Membrane Susceptibility To Natural Killer Cell Mediated Cytotoxicity Leukocyte Mediated Cytotoxicity Brain-derived Neurotrophic Factor Binding Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity	Calpain Complex Calcium-dependent Cysteine-type Endopeptidase Activity Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Endocytosis Thioesterase Binding Positive Regulation Of Phagocytosis Positive Regulation Of Interleukin-8 Production Interleukin-15-mediated Signaling Pathway Interleukin-2-mediated Signaling Pathway Interleukin-9-mediated Signaling Pathway Cytosol Pseudopodium Regulation Of Interleukin-8 Production Cytoplasm Positive Regulation Of Cellular Component Organization Regulation Of Phagocytosis GTPase Activity Regulation Of Endocytosis LncRNA Binding Regulation Of Interleukin-6 Production Calcium-dependent Cysteine-type Endopeptidase Inhibitor Activity Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Establishment Of Endothelial Barrier Positive Regulation Of Interleukin-10 Production Endothelial Cell Development Positive Regulation Of Renin Secretion Into Blood Stream Signal Transduction Involved In Regulation Of Gene Expression Temperature Homeostasis Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly
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