GMFG and CAMK1D

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		GMFG	CAMK1D
Description		glia maturation factor gamma	calcium/calmodulin dependent protein kinase ID
Image
GO Annotations	Cellular Component	Extracellular Region Cortical Actin Cytoskeleton Secretory Granule Lumen Ficolin-1-rich Granule Lumen	Nucleus Cytoplasm
	Molecular Function	Actin Binding Protein Kinase Inhibitor Activity Enzyme Activator Activity Growth Factor Activity Arp2/3 Complex Binding	Nucleotide Binding Catalytic Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Calcium/calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Protein Phosphorylation Signal Transduction Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin Filament Debranching	Inflammatory Response Signal Transduction Nervous System Development Regulation Of Neuron Projection Development Positive Regulation Of Neuron Projection Development Positive Regulation Of CREB Transcription Factor Activity Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Phagocytosis Regulation Of Dendrite Development Positive Regulation Of Respiratory Burst Regulation Of Granulocyte Chemotaxis Positive Regulation Of Neutrophil Chemotaxis
Pathways		Neutrophil degranulation
Drugs			N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE Fostamatinib
Diseases
GWAS		Lung adenocarcinoma ( 28604730)	Anorexia nervosa ( 23568457) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Bipolar disorder ( 31043756) Body mass index ( 28892062) Borderline personality disorder ( 28632202) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery aneurysm in Kawasaki disease ( 27171184) Eating disorders ( 23568457) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Gut microbiota relative abundance (Faecalibacterium) ( 33208821) Headache ( 29397368) Height ( 31562340) Household income (MTAG) ( 31844048) Obesity-related traits ( 23251661) Obstructive sleep apnea (BMI adjusted) ( 33243845) QT interval (drug interaction) ( 23459443) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Tea consumption ( 31046077) Triglyceride levels in HIV infection ( 33109212) Type 2 diabetes ( 30718926 30297969 29358691 26961502 32499647 26818947 22885922 20862305 18372903)
Interacting Genes		5 interacting genes: CAMK1D CEBPA PSD PTGIS VANGL1	14 interacting genes: APP ASAH1 BNIP3L CAMKK1 CDC25A CUL3 GMFG LCK LRRK2 NEDD4 NEDD4L POT1 SNCA TNFSF13
Entrez ID		9535	57118
HPRD ID		06821	06409
Ensembl ID		ENSG00000130755	ENSG00000183049
Uniprot IDs		M0R0C1 M0R1D2 O60234	Q5SQQ7 Q8IU85
PDB IDs		3L50	2JC6 6QP5 6T28 6T29 6T6F 8BFM 8BFS
Enriched GO Terms of Interacting Partners?			Regulation Of Membrane Potential Synapse Organization Positive Regulation Of Catabolic Process Regulation Of Synapse Organization Neuromuscular Junction Development Positive Regulation Of Metabolic Process Positive Regulation Of Endocytosis Regulation Of Protein Catabolic Process Negative Regulation Of Potassium Ion Export Across Plasma Membrane Protein Monoubiquitination Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Protein Catabolic Process Endocytosis Cell Junction Organization Cellular Response To Manganese Ion Sodium Channel Inhibitor Activity Receptor Internalization Postsynapse Potassium Channel Inhibitor Activity Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Monoatomic Cation Transmembrane Transport Positive Regulation Of Programmed Cell Death Response To Manganese Ion Negative Regulation Of Sodium Ion Transport Extracellular Exosome Regulation Of SNARE Complex Assembly Golgi-associated Vesicle Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Protein Metabolic Process Cellular Response To Catecholamine Stimulus Import Into Cell Regulation Of Endocytosis Mitochondrial Membrane Organization Response To Metal Ion Protein Metabolic Process Regulation Of Cell Activation Regulation Of Neurotransmitter Uptake Response To Catecholamine Receptor Catabolic Process Regulation Of Metabolic Process Phospholipase Binding Regulation Of Metal Ion Transport Negative Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Cellular Component Organization Cellular Response To Copper Ion Regulation Of Reactive Oxygen Species Metabolic Process Growth Cone Vesicle-mediated Transport Regulation Of Autophagy
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