OPN4 and ARR3

Number of citations of the paper that reports this interaction (PubMedID 12853434)
56

Data Source:
HPRD (in vitro)

		OPN4	ARR3
Description		opsin 4	arrestin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Axon Dendrite Cell Projection Perikaryon Photoreceptor Disc Membrane Sperm Head Plasma Membrane	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Cell Projection Synapse
	Molecular Function	G Protein-coupled Receptor Activity 11-cis Retinal Binding Protein Binding G Protein-coupled Photoreceptor Activity Photoreceptor Activity	G Protein-coupled Receptor Binding Opsin Binding Protein Binding Phosphoprotein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Visual Perception Phototransduction Optokinetic Behavior Detection Of Visible Light Regulation Of Circadian Rhythm Thermotaxis Rhythmic Process Detection Of Temperature Stimulus Involved In Thermoception Retina Development In Camera-type Eye Cellular Response To Light Stimulus Hyaloid Vascular Plexus Regression	G Protein-coupled Receptor Internalization Endocytosis Signal Transduction Visual Perception
Pathways		G alpha (q) signalling events Opsins
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: ARR3 UBQLN2	20 interacting genes: ADRB2 AP3B1 CAPNS1 CLTC CSNK2A1 DVL2 FSHR GNMT MAP2K7 MARCHF8 OPN1MW OPN4 PLK4 PTAFR RCOR2 RHO RNASE6 SRC ZBTB43 ZNF496
Entrez ID		94233	407
HPRD ID		05977	02358
Ensembl ID		ENSG00000122375	ENSG00000120500
Uniprot IDs		Q9UHM6	P36575
PDB IDs
Enriched GO Terms of Interacting Partners?		Opsin Binding Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of G Protein-coupled Receptor Internalization G Protein-coupled Receptor Internalization Positive Regulation Of ERAD Pathway Negative Regulation Of Receptor Internalization Regulation Of Clathrin-dependent Endocytosis Regulation Of ERAD Pathway Phosphoprotein Binding Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Receptor-mediated Endocytosis Regulation Of Autophagosome Assembly Molecular Condensate Scaffold Activity	Photoreceptor Activity G Protein-coupled Photoreceptor Activity Thermotaxis Photoreceptor Disc Membrane G Protein-coupled Receptor Activity Detection Of Visible Light Sperm Head Plasma Membrane Absorption Of Visible Light Phototransduction Detection Of Temperature Stimulus Involved In Thermoception 11-cis Retinal Binding G Protein-coupled Receptor Signaling Pathway Response To Temperature Stimulus Detection Of Light Stimulus Positive Regulation Of MAPK Cascade Lysosome Transcytosis Regulation Of Organelle Organization Cellular Response To Light Stimulus Detection Of Temperature Stimulus Involved In Sensory Perception Uterus Development Clathrin-coated Endocytic Vesicle Detection Of Temperature Stimulus Bone Resorption Detection Of Abiotic Stimulus Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Response To Light Stimulus Enzyme Binding Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Vacuolar Transport Regulation Of Systemic Arterial Blood Pressure Regulation Of MAPK Cascade Positive Regulation Of Mini Excitatory Postsynaptic Potential Regulation Of Bone Remodeling Regulation Of Bone Resorption Follicle-stimulating Hormone Receptor Activity Regulation Of Acetylcholine Metabolic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Cellular Response To Radiation Rod Bipolar Cell Differentiation RNA Polymerase III General Transcription Initiation Factor Binding Glycine N-methyltransferase Activity Positive Regulation Of ERK1 And ERK2 Cascade Visual Perception Sensory Perception Of Light Stimulus Regulation Of Macroautophagy Response To Radiation Protein Targeting To Vacuole Vasodilation Fc Receptor Signaling Pathway
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