Wiki-MPM
About
Browse
People
Funding
Updates
ZFAND4 and TFAP2C
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
38
Data Source:
BioGRID
(two hybrid)
ZFAND4
TFAP2C
Description
zinc finger AN1-type containing 4
transcription factor AP-2 gamma
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Mitochondrion
Cytosol
Molecular Function
Zinc Ion Binding
Metal Ion Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Inner Cell Mass Cell Differentiation
Trophectodermal Cell Differentiation
Hair Follicle Development
Keratinocyte Development
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Cell-cell Signaling
Male Gonad Development
Stem Cell Population Maintenance
Forebrain Neuron Fate Commitment
Cerebral Cortex Development
Germ-line Stem Cell Population Maintenance
Epithelial Cell Differentiation
Somatic Stem Cell Population Maintenance
Regulation Of Cell Population Proliferation
Skin Development
Regulation Of Epidermis Development
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription By RNA Polymerase II
Sebaceous Gland Development
Stem Cell Differentiation
Dichotomous Subdivision Of Terminal Units Involved In Mammary Gland Duct Morphogenesis
Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation
Morula Formation
Pathways
SUMOylation of transcription factors
Negative regulation of activity of TFAP2 (AP-2) family transcription factors
Negative regulation of activity of TFAP2 (AP-2) family transcription factors
TFAP2 (AP-2) family regulates transcription of other transcription factors
Activation of the TFAP2 (AP-2) family of transcription factors
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors
TFAP2 (AP-2) family regulates transcription of cell cycle factors
Specification of primordial germ cells
Specification of the neural plate border
Specification of the neural plate border
Developmental Lineage of Mammary Stem Cells
Drugs
Diseases
GWAS
Mean corpuscular volume (
29403010
)
Serum alkaline phosphatase levels (
33547301
)
Blond vs. brown/black hair color (
30531825
)
Blood urea nitrogen levels (
31152163
)
Cerebrospinal P-tau181p levels (
28247064
)
Chronic obstructive pulmonary disease (moderate to severe) (
24621683
)
Cognitive decline rate in late mild cognitive impairment (
26252872
)
Maximum stenosis (
32469969
)
Mean degree of stenosis (
32469969
)
Ovarian cancer (
30557369
)
Refractive error (
32231278
)
Sum of stenosis (
32469969
)
Interacting Genes
1 interacting genes:
TFAP2C
13 interacting genes:
BLK
CCNG1
CITED1
CITED2
CITED4
ERBB4
GPR22
IKBKB
NR1I2
TP53
UBE2I
WWOX
ZFAND4
Entrez ID
93550
7022
HPRD ID
16494
03361
Ensembl ID
ENSG00000172671
ENSG00000087510
Uniprot IDs
A8K8Q5
J3KPC0
Q86WR3
Q86XD8
Q92754
PDB IDs
Enriched GO Terms of Interacting Partners
?
Inner Cell Mass Cell Differentiation
Morula Formation
Sebaceous Gland Development
Forebrain Neuron Fate Commitment
Germ-line Stem Cell Population Maintenance
Dichotomous Subdivision Of Terminal Units Involved In Mammary Gland Duct Morphogenesis
Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation
Keratinocyte Development
Mammary Gland Epithelial Cell Proliferation
Trophectodermal Cell Differentiation
Neuron Fate Commitment
Hair Follicle Development
Skin Development
Somatic Stem Cell Population Maintenance
Regulation Of Epidermis Development
Hair Cycle Process
Cerebral Cortex Development
Male Gonad Development
Stem Cell Differentiation
Stem Cell Population Maintenance
Maintenance Of Cell Number
Epithelial Cell Development
Gonad Development
Epithelial Cell Proliferation
Negative Regulation Of Gene Expression, Epigenetic
Cell Fate Commitment
Reproductive Structure Development
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Metabolic Process
LBD Domain Binding
Response To Estrogen
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Enzyme-linked Receptor Protein Signaling Pathway
Regulation Of DNA-templated Transcription
Positive Regulation Of Signal Transduction
Response To Growth Factor
Regulation Of RNA Biosynthetic Process
Transcription Coactivator Activity
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of RNA Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Transcription By RNA Polymerase II
Molecular Function Activator Activity
Positive Regulation Of Biosynthetic Process
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Regulation Of Nucleobase-containing Compound Metabolic Process
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Primary Metabolic Process
Cell Differentiation
Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Macromolecule Metabolic Process
Establishment Of Planar Polarity Involved In Nephron Morphogenesis
Negative Regulation Of Helicase Activity
Negative Regulation Of G1 To G0 Transition
SUMO Conjugating Enzyme Activity
Nuclear Transport
Nucleocytoplasmic Transport
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Signal Transduction
Response To Hormone
Tumor Necrosis Factor-mediated Signaling Pathway
Regulation Of Transcription By RNA Polymerase II
Heart Development
Regulation Of Macromolecule Metabolic Process
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Intracellular Signal Transduction
Apoptotic Mitochondrial Changes
Vasculogenesis
Cellular Senescence
Intracellular Signal Transduction
Regulation Of Cell Communication
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?