IGSF8 and KRTAP10-4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		IGSF8	KRTAP10-4
Description		immunoglobulin superfamily member 8	keratin associated protein 10-4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Presynaptic Membrane Extracellular Exosome Hippocampal Mossy Fiber To CA3 Synapse	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding Signaling Receptor Activity	Protein Binding
	Biological Process	Single Fertilization Nervous System Development Skeletal Muscle Tissue Development Positive Regulation Of Cell Migration Cell Motility Regulation Of Cell Motility
Pathways			Keratinization
Drugs
Diseases
GWAS			Leukocyte telomere length ( 32109421)
Interacting Genes		20 interacting genes: A2M CD47 CD81 CD82 CD9 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-4 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-12 KRTAP5-7 NBPF19 NOTCH2NLA SLIT3 TGM1	11 interacting genes: CATSPER1 E4F1 HOXA1 IGSF8 JOSD1 OTX1 RSPO2 WT1 ZNF32 ZNF625 ZSCAN26
Entrez ID		93185	386672
HPRD ID		09438	11190
Ensembl ID		ENSG00000162729	ENSG00000215454
Uniprot IDs		Q969P0	P60372
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Myoblast Fusion Involved In Skeletal Muscle Regeneration Cellular Response To Lipoprotein Particle Stimulus Myoblast Fusion Regulation Of Mononuclear Cell Migration Cell-cell Fusion Cellular Response To Low-density Lipoprotein Particle Stimulus Syncytium Formation Syncytium Formation By Plasma Membrane Fusion Macrophage Fusion Positive Regulation Of Adaptive Immune Memory Response CD4-positive, Alpha-beta T Cell Costimulation Regulation Of Macrophage Migration	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Tube Morphogenesis Semicircular Canal Formation Sequence-specific Double-stranded DNA Binding Abducens Nerve Formation Optokinetic Behavior Diencephalon Morphogenesis Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Adrenal Cortex Formation Positive Regulation Of Metanephric Ureteric Bud Development Regulation Of Animal Organ Morphogenesis Visceral Serous Pericardium Development Posterior Mesonephric Tubule Development Negative Regulation Of Odontogenesis Of Dentin-containing Tooth Lung Growth Regulation Of RNA Metabolic Process Metencephalon Development Negative Regulation Of Female Gonad Development Negative Regulation Of Glomerular Mesangial Cell Proliferation Trachea Cartilage Morphogenesis Embryonic Morphogenesis Regulation Of Mitotic Cell Cycle, Embryonic Hemi-methylated DNA-binding Metanephric S-shaped Body Morphogenesis Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cell Proliferation Involved In Kidney Development Thorax And Anterior Abdomen Determination Branching Morphogenesis Of An Epithelial Tube Double-stranded Methylated DNA Binding S-shaped Body Morphogenesis Zinc Ion Binding Embryonic Neurocranium Morphogenesis Anterior/posterior Pattern Specification Diaphragm Development Regulation Of Female Gonad Development Morphogenesis Of A Branching Structure Positive Regulation Of Male Gonad Development Morphogenesis Of A Branching Epithelium Cardiac Muscle Cell Fate Commitment Metanephric Mesenchyme Development Membrane Biogenesis CatSper Complex Outer Ear Morphogenesis
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