DLGAP1 and DLGAP3

Number of citations of the paper that reports this interaction (PubMedID 9115257)
0

Data Source:
HPRD (two hybrid, in vivo)

		DLGAP1	DLGAP3
Description		DLG associated protein 1	DLG associated protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Postsynaptic Density Membrane Synapse Glutamatergic Synapse Postsynaptic Specialization	Plasma Membrane Postsynaptic Density Membrane Neuromuscular Junction Synapse Glutamatergic Synapse Cholinergic Synapse Postsynaptic Specialization
	Molecular Function	Protein Binding Protein-containing Complex Binding Molecular Adaptor Activity	Amyloid-beta Binding Protein Binding Molecular Adaptor Activity
	Biological Process	Chemical Synaptic Transmission Signaling Modulation Of Chemical Synaptic Transmission	Signaling Modulation Of Chemical Synaptic Transmission Modification Of Postsynaptic Structure
Pathways		Neurexins and neuroligins Neurexins and neuroligins	Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 31219225) Body fat mass ( 28552196) Cardiac Troponin-T levels ( 23247143) Eating disorders ( 22911880) Economic and political preferences (time) ( 22566634) Erythrocyte cadmium concentration in never smokers ( 27005419) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hip circumference adjusted for BMI ( 28552196) Initial alcohol sensitivity ( 30276832) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Menarche (age at onset) ( 27182965 25231870) Midgestational circulating levels of PBDEs ( 28235828) Mild age-related type 2 diabetes ( 34737425) Obesity-related traits ( 23251661) Plasma free amino acid levels ( 30659259) Response to fenofibrate (total cholesterol levels) ( 27002377) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Trunk fat mass ( 28552196) Upper eyelid sagging severity ( 24869959)	Glomerular filtration rate in chronic kidney disease ( 26420894) Nicotine dependence ( 28440896)
Interacting Genes		24 interacting genes: APC DLG1 DLG2 DLG3 DLG4 DLGAP2 DLGAP3 DYNLL1 DYNLL2 FHL2 GRB2 GRIN2A GRIN2C ITSN1 ITSN2 KCNA4 MAGEA11 MAGI2 MYO5A SHANK1 SHANK2 SHANK3 SORBS2 TANC1	15 interacting genes: DLG1 DLG2 DLG3 DLG4 DLGAP1 GOLGA2 KANK2 KRTAP1-3 KRTAP5-2 MAGEA6 MAGI2 PTK2 PTK2B SHANK2 SHANK3
Entrez ID		9229	58512
HPRD ID		09260	18935
Ensembl ID		ENSG00000170579	ENSG00000116544
Uniprot IDs		A0A0A0MTP4 A0A9L9PY43 A8MXQ8 B7Z2J5 O14490 Q6IS01	O95886
PDB IDs		5YPO 6TNQ 6TQ0
Enriched GO Terms of Interacting Partners?		Postsynaptic Density Ionotropic Glutamate Receptor Binding Neuron Projection Protein Localization To Synapse Synapse Protein Localization To Cell Junction Receptor Clustering Glutamatergic Synapse Protein Localization To Membrane Positive Regulation Of Excitatory Postsynaptic Potential Dendritic Spine Postsynaptic Density Membrane Modulation Of Excitatory Postsynaptic Potential Plasma Membrane Synaptic Receptor Adaptor Activity Vocalization Behavior Localization Within Membrane Scaffold Protein Binding Learning Neuromuscular Junction Ionotropic Glutamate Receptor Signaling Pathway Protein Localization To Postsynaptic Membrane Dendritic Spine Organization Protein Localization To Postsynapse Chemical Synaptic Transmission Associative Learning Cellular Localization Modulation Of Chemical Synaptic Transmission Trans-synaptic Signaling Ligand-gated Ion Channel Signaling Pathway Synaptic Signaling Neuron Projection Organization Postsynapse Organization Neuromuscular Process Receptor Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Neuromuscular Process Controlling Balance Regulation Of Nervous System Process Postsynaptic Membrane Glutamate Receptor Signaling Pathway Establishment Or Maintenance Of Apical/basal Cell Polarity Social Behavior Regulation Of Neuronal Synaptic Plasticity Signaling Positive Regulation Of Synaptic Transmission Regulation Of Membrane Potential Learning Or Memory Clathrin-dependent Synaptic Vesicle Endocytosis Dendritic Spine Morphogenesis Postsynaptic Density Organization	Ionotropic Glutamate Receptor Binding Receptor Clustering Postsynaptic Density Neuron Projection Receptor Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Protein Localization To Membrane Protein Localization To Synapse Establishment Or Maintenance Of Cell Polarity Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Neuromuscular Junction Protein Localization To Cell Junction Vocalization Behavior Protein Kinase Binding Kinase Binding Postsynaptic Density Membrane Beta-1 Adrenergic Receptor Binding Positive Regulation Of Excitatory Postsynaptic Potential Localization Within Membrane Synaptic Receptor Adaptor Activity Chemical Synaptic Transmission Synapse Positive Regulation Of Synaptic Transmission Trans-synaptic Signaling AMPA Glutamate Receptor Clustering Synaptic Signaling Modulation Of Excitatory Postsynaptic Potential Phosphatase Binding Social Behavior Adherens Junction Neuron Spine Signal Complex Assembly Regulation Of Synaptic Plasticity GMP Kinase Activity GDP Metabolic Process Cell Projection Juxtaparanode Region Of Axon Modulation Of Chemical Synaptic Transmission Regulation Of Cell Morphogenesis Regulation Of Cellular Component Size Neurotransmitter-gated Ion Channel Clustering Regulation Of Cytoskeleton Organization Cellular Response To Potassium Ion Regulation Of Actin Filament Organization Glutamatergic Synapse Regulation Of Biological Quality Nervous System Development Dendritic Spine Morphogenesis Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
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