LONRF1 and KRTAP19-6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LONRF1	KRTAP19-6
Description		LON peptidase N-terminal domain and ring finger 1	keratin associated protein 19-6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Cytosol Intermediate Filament
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Keratinization
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Colorectal cancer (diet interaction) ( 24743840) HDL cholesterol levels ( 32203549)
Interacting Genes		98 interacting genes: ADAMTSL4 ALAS1 AP2B1 ATG9A AVPI1 BRCA1 BYSL C4orf17 CALCOCO2 CBLL2 CDKN2D CFP CRX CYSRT1 DSCR9 DVL3 EFHC2 FLACC1 GABPB2 GORASP1 GORASP2 GPRASP3 HLX HOXA1 HSPB1 IHO1 IKZF2 IKZF3 IQCF2 KAT5 KATNBL1 KCTD21 KCTD9 KHDC1 KRT31 KRT35 KRT75 KRTAP1-3 KRTAP13-1 KRTAP13-3 KRTAP19-6 KRTAP19-7 KRTAP3-3 KRTAP6-1 LGALS9B LHX2 LHX4 LNX1 MAGED1 MGAT5B MID2 MRPL38 MTMR3 MYOZ3 NR4A1 NTAQ1 OOEP PATZ1 PAX5 PAX6 PAX8 PICK1 PLSCR1 POU6F2 PPP1R3C PRDM16 PRDM6 PRR35 PSMA1 RBPMS RIMBP3C RPRD1A RSPH1 SFN SLU7 SPRY2 STAU1 STX11 TASOR2 TBX19 TRAF2 TRIM27 TRIM42 TRIM8 TRIM9 UBE2I UBE2L6 UCHL3 USP2 VGLL1 WDR83 XIAP YPEL3 ZFP90 ZNF426 ZNF653 ZNF774 ZNHIT2	69 interacting genes: ATOSB ATPAF2 BCAS2 C11orf16 CATSPER1 CCDC24 CCNK CERK CIMIP1 CREB5 CRY2 CSKMT CYSRT1 DMRTB1 DTX2 ENKD1 FANCL FNDC11 FOXH1 GPANK1 GUCD1 HOXA1 HSF4 INCA1 KIFC3 KPRP KRTAP12-4 KRTAP26-1 KRTAP6-3 KRTAP9-3 LASP1 LONRF1 MEIS2 MGAT5B MKRN3 MYOZ3 MYPOP NOC4L NTAQ1 OIP5 OTX1 PATZ1 PLAC8 PLEKHN1 PLSCR3 PLSCR4 POU4F2 PROP1 PSMB2 RBPMS2 RHOXF2 RUNX1T1 SAXO4 SLC25A18 SMN1 SMN2 SNRPB SNRPC SPAG8 SPMIP6 TEKT4 TEKT5 TENT5B TFAP2D TSPYL6 VENTX VGLL3 VPS37C ZNF414
Entrez ID		91694	337973
HPRD ID		08674	11210
Ensembl ID		ENSG00000154359	ENSG00000186925
Uniprot IDs		Q17RB8	A4FU57 Q3LI70
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding Zinc Ion Binding Protein Modification By Small Protein Conjugation Protein Ubiquitination Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Identical Protein Binding Keratin Filament Post-translational Protein Modification Positive Regulation Of RNA Metabolic Process Ubiquitin Protein Ligase Activity Regulation Of DNA-templated Transcription Transcription Coactivator Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Protein Kinase C Inhibitor Activity Negative Regulation Of Viral Transcription Suppression Of Viral Release By Host Positive Regulation Of Biosynthetic Process Regulation Of Viral Transcription Regulation Of RNA Metabolic Process Protein Modification Process Establishment Of Spindle Localization Structural Constituent Of Skin Epidermis RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Spindle Localization Non-canonical Inflammasome Complex Assembly Telencephalon Regionalization Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Cellular Response To Vascular Endothelial Growth Factor Stimulus Outer Dense Fiber Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Cytosol Protein K63-linked Ubiquitination Negative Regulation Of Viral Process Positive Regulation Of Macromolecule Metabolic Process Nucleus	Axonemal A Tubule Inner Sheath Protein Binding Sperm Flagellum Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility Chromatin Spliceosomal SnRNP Assembly SMN-Sm Protein Complex Nucleus Cilium Movement Cajal Body Motile Cilium DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cilium SMN Complex Spliceosomal Complex Assembly
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