UBXN11 and RND1

Number of citations of the paper that reports this interaction (PubMedID 11940653)
29

Data Source:
BioGRID (pull down, affinity chromatography technology, biochemical)
HPRD (in vivo, two hybrid, in vitro)

		UBXN11	RND1
Description		UBX domain protein 11	Rho family GTPase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Actin Cytoskeleton Membrane
	Molecular Function	Protein Binding Ubiquitin Binding	Nucleotide Binding GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Actin Filament Organization Negative Regulation Of Cell Adhesion Signal Transduction Small GTPase-mediated Signal Transduction Neuron Remodeling Regulation Of Actin Cytoskeleton Organization
Pathways		RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle	SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse RND1 GTPase cycle
Drugs
Diseases
GWAS		Monocyte percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Platelet count ( 32888494)	Bipolar disorder ( 21926972)
Interacting Genes		34 interacting genes: C14orf119 CFAP206 EIF4E EIF4E2 ENKD1 HGS IL16 LENG1 NEK6 PPM1K PRKAA1 PRKAB2 PRPF18 PRPF31 PRR35 PSMA1 RHOBTB3 RND1 RND2 RND3 RNF213 SCNM1 SH2D4A SNRPB TCEANC TLE5 TRAF2 TTC23 USHBP1 VCP VPS9D1 WDR25 ZFYVE9 ZGPAT	23 interacting genes: ARFIP2 CCNI COPS2 CREB3L2 EEF1A1 FRS2 FRS3 GPX8 GRB7 ID3 KRT6A MYH7 MYOM3 MYZAP NEDD1 PAIP1 PDE6D PLXNA1 PLXNB1 PLXNB2 SHMT2 UBXN11 ZNF212
Entrez ID		91544	27289
HPRD ID		10245	12357
Ensembl ID		ENSG00000158062	ENSG00000172602
Uniprot IDs		Q5T124	Q92730
PDB IDs			2CLS 2REX 3Q3J
Enriched GO Terms of Interacting Partners?		Nuclear Speck MRNA Cap Binding SnRNP Binding AMP-activated Protein Kinase Activity U4/U6 X U5 Tri-snRNP Complex Protein Binding Protein Kinase Binding RNA Cap Binding RNA 7-methylguanosine Cap Binding Eukaryotic Translation Initiation Factor 4F Complex Nucleotide-activated Protein Kinase Complex U4 SnRNP Ubiquitin Protein Ligase Binding Spliceosomal Complex Organelle Disassembly	Semaphorin Receptor Complex Semaphorin Receptor Activity Semaphorin-plexin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Synapse Assembly
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