KRT75 and TJAP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT75	TJAP1
Description		keratin 75	tight junction associated protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Cytoplasm Endosome Golgi Apparatus Trans-Golgi Network Plasma Membrane Bicellular Tight Junction Membrane Anchoring Junction
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding
	Biological Process	Hematopoietic Progenitor Cell Differentiation Keratinization Intermediate Filament Organization	Golgi Organization
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases		Pseudofolliculitis barbae
GWAS			PR interval in Tripanosoma cruzi seropositivity ( 24324551) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		119 interacting genes: - ABI2 AIRIM AMOT ANKS1A ARMC7 ASB15 BCAS2 BEX2 C19orf25 C1orf216 CAMK2A CARD10 CARD9 CATSPERT CCDC102B CCDC197 CCHCR1 CDC37 CDK18 CDKN2D CEP57 CFAP206 CPNE7 CRACR2A DHX15 DMAP1 DTNBP1 DYDC1 EFHC1 EPM2AIP1 FBXO17 FKBP6 GLYCTK GMCL1 GOLGA2 GOLGA6L9 GPANK1 HGS HNRNPF INCA1 IQUB KANK2 KCTD7 KIF9 KIFC3 KRT13 KRT20 KRT24 KRT25 KRT26 KRT27 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 KRT76 LCA5L LMO1 LMO2 LMO4 LONRF1 MAGOHB MID2 MKRN3 MNS1 MTUS2 MYO15B MYOZ3 NCDN NDC80 NEK6 NFKBID NME7 NUDT21 NUP62 OIP5 OSGIN1 PLEKHG4 PM20D2 POLR1C POLR3C RCOR3 RSPH14 SCNM1 SMARCD1 SPAG5 SPTA1 STX11 SUFU TBC1D1 TCHP TEKT1 TEKT4 TJAP1 TNPO2 TNPO3 TRAF1 TRIM23 TRIM27 TRIM54 TRIML2 TSG101 TSSK3 TXLNA TXLNB U2AF1 USHBP1 WASHC1 WASHC3 WWOX XPOT ZNF76 ZWINT	7 interacting genes: APBA1 DLG1 DLG4 GOLGA6L9 KRT75 MEOX2 TRIM54
Entrez ID		9119	93643
HPRD ID		11057	10269
Ensembl ID		ENSG00000170454	ENSG00000137221
Uniprot IDs		O95678	Q5JTD0
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Keratin Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Structural Molecule Activity Supramolecular Fiber Organization Cytoskeleton Organization Protein Binding Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Motile Cilium Organelle Organization Axonemal A Tubule Inner Sheath Radial Spoke Microtubule-based Process Sperm Flagellum Axonemal Microtubule Cytoplasm Microtubule-based Movement Flagellated Sperm Motility Sperm Motility Cytosol Cilium-dependent Cell Motility Cilium Movement Cilium Movement Involved In Cell Motility Cilium Identical Protein Binding Microtubule Binding Regulation Of Actin Nucleation Microtubule Regulation Of Organelle Organization Spliceosomal Complex CBM Complex Centrosome Regulation Of Arp2/3 Complex-mediated Actin Nucleation Phosphatidylinositol 3-kinase Inhibitor Activity Polymeric Cytoskeletal Fiber Spindle Organization	Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse Ionotropic Glutamate Receptor Binding Chemical Synaptic Transmission Receptor Localization To Synapse Receptor Clustering Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Trans-synaptic Signaling Protein Localization To Synapse Synaptic Signaling Synaptic Membrane Protein-containing Complex Localization Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels P2Y1 Nucleotide Receptor Binding Neuromuscular Junction Protein Localization To Cell Junction Kinase Binding Postsynaptic Density Membrane Nervous System Development Glutamatergic Synapse Structural Constituent Of Postsynaptic Density L27 Domain Binding Beta-1 Adrenergic Receptor Binding Regulation Of Grooming Behavior Synaptic Vesicle Cell-cell Signaling Cell Communication Dendritic Spine Signaling MPP7-DLG1-LIN7 Complex Maintenance Of Postsynaptic Density Structure Lateral Loop Myelin Sheath Abaxonal Region Muscle Tissue Development Establishment Or Maintenance Of Cell Polarity AMPA Glutamate Receptor Clustering Neuroligin Family Protein Binding Somite Specification Gamma-aminobutyric Acid Secretion Regulation Of Potassium Ion Import Adherens Junction NMDA Selective Glutamate Receptor Signaling Pathway Locomotory Behavior Cell Junction D1 Dopamine Receptor Binding Microtubule-based Process Cerebellar Mossy Fiber Synaptic Vesicle Maturation
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