TGIF2LY and NAB2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		TGIF2LY	NAB2
Description		TGFB induced factor homeobox 2 like Y-linked	NGFI-A binding protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding	Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription	Endochondral Ossification Regulation Of DNA-templated Transcription Schwann Cell Differentiation Negative Regulation Of Transcription By RNA Polymerase III Myelination Regulation Of Epidermis Development Negative Regulation Of DNA-templated Transcription
Pathways			NGF-stimulated transcription NGF-stimulated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 29273806 31361310 31619474 31959851) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Bipolar disorder ( 31043756) IgE levels ( 22075330) Schizophrenia ( 25056061 29483656)
Interacting Genes		3 interacting genes: MBIP NAB2 PCBD2	87 interacting genes: ANK3 ANKRD11 APH1B CBX8 CCDC187 CCDC33 CCDC57 CCHCR1 CDC23 CTAG1A CTAG1B CTNNA3 CWF19L2 DDX6 DGCR6 DGCR6L DRG2 EGR1 EGR2 ELOA ENKD1 EXOC8 FAM200C FAM9A GCC1 GOLGA6L9 HOXA10 HRH1 HSF2BP JAKMIP2 KIF9 KIFC3 KRT34 KRT40 KRTAP10-3 KRTAP10-8 LENG1 LMNA LNX1 LRP1 MAPK3 MCM7 MCRS1 MDFI MORF4L1 MORF4L2 MYO1A NDOR1 NEDD9 NME7 NOTCH2NLA NTAQ1 PHF1 PHOSPHO2 PIK3R3 PIN1 PLOD3 PRKAA2 PRKAB2 PSMA1 QARS1 RBPMS RDH5 RFC5 RINT1 SCN1A SCNM1 SMARCD1 SORBS3 SPG21 SUMO1P1 TCEA2 TCEANC TCHP TGIF2LY TLE5 TRAF2 TRIM23 TSGA10 TSGA10IP TTC19 USP2 UTP14C ZMAT2 ZMYND12 ZMYND19 ZNF417
Entrez ID		90655	4665
HPRD ID		18512	03854
Ensembl ID		ENSG00000176679	ENSG00000166886
Uniprot IDs		Q8IUE0	Q15742
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription By RNA Polymerase III Schwann Cell Differentiation 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Tetrahydrobiopterin Biosynthetic Process Tetrahydrobiopterin Metabolic Process ATAC Complex Pteridine-containing Compound Biosynthetic Process Endochondral Ossification Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase III Diol Metabolic Process Pteridine-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Protein Kinase Inhibitor Activity
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