NAV2 and RBM15

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		NAV2	RBM15
Description		neuron navigator 2	RNA binding motif protein 15
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GO Annotations	Cellular Component	Interstitial Matrix Nucleus Nucleoplasm Extracellular Matrix	Nucleus Nuclear Envelope Nucleoplasm Membrane Nuclear Speck Nuclear Membrane RNA N6-methyladenosine Methyltransferase Complex
	Molecular Function	Nucleotide Binding Helicase Activity Protein Binding ATP Binding Heparin Binding Hydrolase Activity ATP Hydrolysis Activity 3'-5' DNA Helicase Activity	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Nervous System Development Sensory Perception Of Sound Sensory Perception Of Smell Locomotory Behavior Optic Nerve Development Glossopharyngeal Nerve Development Vagus Nerve Development Cerebellar Cortex Development Neurogenesis	Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Methylation Branching Involved In Blood Vessel Morphogenesis Positive Regulation Of Transcription Of Notch Receptor Target Dosage Compensation By Inactivation Of X Chromosome Thrombopoietin-mediated Signaling Pathway Regulation Of Myeloid Cell Differentiation Negative Regulation Of Myeloid Cell Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of DNA-templated Transcription Spleen Development Ventricular Septum Morphogenesis Placenta Blood Vessel Development
Pathways
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Atrial fibrillation ( 29892015 30061737) Bone mineral density x blood lead interaction in current smokers (2df test) ( 29518117) Brain morphology (MOSTest) ( 32665545) Coronary artery aneurysm in Kawasaki disease ( 27171184) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) General cognitive ability ( 29844566) Hepatitis ( 25705159) L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Lateral thalamic nuclei volume ( 34006833) Low susceptibility to hepatitis C infection ( 31206233) Macular thickness ( 30535121) Monobrow ( 27182965) Obesity-related traits ( 23251661) PR interval ( 32439900 30046033) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762) Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627) Smoking initiation (ever regular vs never regular) ( 30679032) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306) Waist circumference ( 28552196)
Interacting Genes		12 interacting genes: ADAT2 APC CFAP58 ING4 ING5 MORF4L1 PIAS2 PRPF3 PSTPIP1 RBM15 RBM15B RRAS	18 interacting genes: ABI1 AZGP1P2 CALCOCO2 CD2 CEBPA CEP44 CLK1 CNOT4 CTTN DDX17 KRT31 LZTS2 MAPK8 NAV2 PRMT1 SRPK2 TSPYL2 USP7
Entrez ID		89797	64783
HPRD ID		07385	05832
Ensembl ID		ENSG00000166833	ENSG00000162775
Uniprot IDs		A7E2D6 Q8IVL1	Q96T37
PDB IDs		2YRN	7Z27
Enriched GO Terms of Interacting Partners?		DNA Replication-dependent Chromatin Disassembly Nuclear Speck RNA N6-methyladenosine Methyltransferase Complex Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Histone H3K4me3 Reader Activity Histone Acetyltransferase Complex Chromatin Organization RNA Modification Nucleoplasm Protein Acetylation Fibroblast Proliferation TRNA Wobble Adenosine To Inosine Editing TRNA-specific Adenosine-34 Deaminase Activity Macromolecule Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Nucleic Acid Metabolic Process RNA Methylation Regulation Of DNA Biosynthetic Process RNA Metabolic Process
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