USP13 and FNBP1L

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		USP13	FNBP1L
Description		ubiquitin specific peptidase 13	formin binding protein 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell Cortex Membrane Cytoplasmic Vesicle
	Molecular Function	Cysteine-type Endopeptidase Activity Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Zinc Ion Binding Hydrolase Activity Ubiquitin Protein Ligase Binding Ubiquitin Binding Ubiquitin-like Protein Ligase Binding Metal Ion Binding Protein-folding Chaperone Binding Proteasome Binding BAT3 Complex Binding K48-linked Deubiquitinase Activity	Protein Binding Lipid Binding Cadherin Binding GTPase Binding
	Biological Process	Regulation Of DNA-templated Transcription Proteolysis Autophagy Cell Population Proliferation Regulation Of Autophagy Protein Deubiquitination Melanocyte Differentiation Regulation Of Protein Stability Protein K29-linked Deubiquitination Maintenance Of Unfolded Protein Protein K6-linked Deubiquitination Protein Stabilization Protein K63-linked Deubiquitination Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of ERAD Pathway	Endocytosis Vesicle Budding From Membrane Autophagy Signal Transduction Membrane Invagination Vesicle Organization Vesicle Transport Along Actin Filament Positive Regulation Of Filopodium Assembly Cilium Assembly Clathrin-dependent Endocytosis Plasma Membrane Tubulation
Pathways		Ub-specific processing proteases Regulation of PTEN stability and activity	Clathrin-mediated endocytosis CDC42 GTPase cycle RHOJ GTPase cycle
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) High density lipoprotein cholesterol levels ( 33339817) Liver enzyme levels (alanine transaminase) ( 33972514) Triglyceride levels ( 29403010 33339817)
Interacting Genes		30 interacting genes: AMFR ATG5 CCND1 CLK3 CSNK2A1 CTNNB1 DAZAP2 DVL1 DYRK1A FNBP1L FUNDC2 G3BP1 GPR160 HSP90AA1 LAPTM5 MDC1 MRPL20 MYO15A S100A9 SIAH2 SPRR2C SYCP2 TOPBP1 TRA2B TRIM55 TRIM63 TWIST1 UBC UBL4A UIMC1	6 interacting genes: ACP1 CDC42 DNM2 SGSM2 USP13 WASL
Entrez ID		8975	54874
HPRD ID		04666	12317
Ensembl ID		ENSG00000058056	ENSG00000137942
Uniprot IDs		A0A0A6YZ17 Q92995	B4DSI7 Q5T0N5
PDB IDs		2L80 2LBC
Enriched GO Terms of Interacting Partners?		DNA Damage Checkpoint Signaling Protein Modification Process Wnt Signaling Pathway Protein Ubiquitination Mitotic DNA Integrity Checkpoint Signaling Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Signaling Negative Regulation Of Autophagic Cell Death Autophagy Protein Localization To Site Of Double-strand Break Protein Modification By Small Protein Conjugation Regulation Of Protein Ubiquitination Intracellular Signal Transduction Negative Regulation Of Cell Cycle Negative Regulation Of Mitotic Cell Cycle Protein Metabolic Process Negative Regulation Of Cell Cycle Phase Transition Regulation Of Post-translational Protein Modification Chaperone-mediated Autophagy Positive Regulation Of Stress Granule Assembly Negative Regulation Of Signal Transduction By P53 Class Mediator Post-translational Protein Modification Response To Stress Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cell Cycle Process Identical Protein Binding Negative Regulation Of Programmed Cell Death Regulation Of Programmed Cell Death Double-strand Break Repair Via Nonhomologous End Joining Double-strand Break Repair Via Classical Nonhomologous End Joining Regulation Of Stress Granule Assembly Ubiquitin Protein Ligase Binding Regulation Of DNA Metabolic Process Genitalia Morphogenesis Regulation Of Wnt Signaling Pathway Cellular Response To Stress Negative Regulation Of Wnt Signaling Pathway Wnt Signalosome Cardiac Muscle Cell Apoptotic Process Catabolic Process Protein Serine/threonine Kinase Activator Activity Nucleus Aggrephagy Striated Muscle Cell Apoptotic Process Macromolecule Metabolic Process Regulation Of Cellular Response To Stress Protein-containing Complex Macromolecule Catabolic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Catabolic Process	Negative Regulation Of Membrane Tubulation Dendritic Spine Morphogenesis Regulation Of Plasma Membrane Organization Cell Projection Morphogenesis Actin Filament Organization Positive Regulation Of Filopodium Assembly Establishment Of Organelle Localization Neuron Projection Morphogenesis Dendritic Spine Organization Vesicle Budding From Membrane Neuron Projection Organization Postsynapse Organization Regulation Of Filopodium Assembly Actin Cytoskeleton Organization Actin Filament-based Process Endocytic Vesicle Membrane Protein Polymerization Organelle Localization Supramolecular Fiber Organization Establishment Of Vesicle Localization SH3 Domain Binding Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly GBD Domain Binding Storage Vacuole Vesicle Scission Vesicle Localization Establishment Of Localization In Cell Hydrolase Activity Membrane Organization Regulation Of Postsynapse Organization Endothelin Receptor Signaling Pathway Involved In Heart Process Protein K6-linked Deubiquitination Positive Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Cellular Component Organization Positive Regulation Of Endocytosis Apolipoprotein A-I Receptor Binding Neuropilin Signaling Pathway Protein K29-linked Deubiquitination Maintenance Of Unfolded Protein BAT3 Complex Binding Actin Cap Midbody Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Cytoskeleton-dependent Intracellular Transport Acid Phosphatase Activity Membrane Tubulation Vesicle Transport Along Actin Filament Late Endosome To Golgi Transport Cytoplasmic Vesicle Positive Regulation Of Pinocytosis
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