WHR1 and SLC29A1

Number of citations of the paper that reports this interaction (PubMedID 14667819)
0

Data Source:
HPRD (two hybrid)

		WHR1	SLC29A1
Description		winged helix repair factor 1	solute carrier family 29 member 1 (Augustine blood group)
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Nuclear Speck	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Presynapse Postsynapse
	Molecular Function	DNA Binding Double-stranded DNA Binding RNA Binding Double-stranded RNA Binding Protein Serine/threonine Kinase Activity Protein Binding Protein Homodimerization Activity	Neurotransmitter Transmembrane Transporter Activity Nucleoside Transmembrane Transporter Activity Adenine Transmembrane Transporter Activity Guanine Transmembrane Transporter Activity Uracil Transmembrane Transporter Activity Purine Nucleoside Transmembrane Transporter Activity Cytidine Transmembrane Transporter Activity Uridine Transmembrane Transporter Activity Pyrimidine- And Adenosine-specific:sodium Symporter Activity
	Biological Process	DNA Repair DNA Damage Response Positive Regulation Of Ras Protein Signal Transduction Positive Regulation Of Single Strand Break Repair	Neurotransmitter Uptake Nucleobase-containing Compound Metabolic Process Xenobiotic Metabolic Process Neurotransmitter Transport Xenobiotic Transmembrane Transport Lactation Nucleobase Transport Adenine Transport Nucleoside Transport Purine Nucleoside Transmembrane Transport Cytidine Transport Uridine Transmembrane Transport Adenosine Transport Inosine Transport Hypoxanthine Transport Thymine Transport Excitatory Postsynaptic Potential Cellular Response To Glucose Stimulus Cellular Response To Hypoxia Pyrimidine-containing Compound Transmembrane Transport Transport Across Blood-brain Barrier Nucleoside Transmembrane Transport Guanine Transmembrane Transport Uracil Transmembrane Transport Pyrimidine Nucleobase Transmembrane Transport Purine Nucleobase Transmembrane Transport
Pathways			Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane Azathioprine ADME Ribavirin ADME
Drugs			Troglitazone Ethanol Fostamatinib
Diseases
GWAS			Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		13 interacting genes: BHLHE40 MAB21L3 PFDN5 PICK1 POLE POLR2G PRAME SF3B4 SLC29A1 SP3 TBRG4 TRIM23 VIM	4 interacting genes: BCS1L CREB3 HTR2C WHR1
Entrez ID		8859	2030
HPRD ID		07281	03724
Ensembl ID		ENSG00000204344	ENSG00000112759
Uniprot IDs		A0A1U9X8L3 P49842	Q99808
PDB IDs		7XRB 8YCM 9BZ0 9ER2 9FD2	6OB6 6OB7 8TZI
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Single Strand Break Repair Positive Regulation Of Deacetylase Activity 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Binding Protein Insertion Into Mitochondrial Inner Membrane From Matrix Gq/11-coupled Serotonin Receptor Activity Positive Regulation Of Phosphatidylinositol Biosynthetic Process G Protein-coupled Serotonin Receptor Complex Regulation Of Corticotropin-releasing Hormone Secretion Release From Viral Latency CCR1 Chemokine Receptor Binding Respiratory Chain Complex III Mitochondrial Respiratory Chain Complex III Assembly Serotonin Binding Phospholipase C-activating Serotonin Receptor Signaling Pathway Serotonin Receptor Signaling Pathway CAMP Response Element Binding Protein Binding Positive Regulation Of Phospholipid Biosynthetic Process Serotonin Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Insertion Into Mitochondrial Inner Membrane Regulation Of Phospholipid Biosynthetic Process Neurotransmitter Receptor Activity Positive Regulation Of Ras Protein Signal Transduction Induction Of Positive Chemotaxis Mitochondrial Cytochrome C Oxidase Assembly G Protein-coupled Serotonin Receptor Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Respiratory Chain Complex IV Assembly Regulation Of Intracellular Signal Transduction Regulation Of Appetite Regulation Of Cellular Response To Stress Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Positive Chemotaxis
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