CCK and MEP1A

Number of citations of the paper that reports this interaction (PubMedID 11278902)
0

Data Source:
HPRD (in vitro)

		CCK	MEP1A
Description		cholecystokinin	meprin A subunit alpha
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Axon	Extracellular Space Plasma Membrane Membrane Meprin A Complex Extracellular Exosome
	Molecular Function	Hormone Activity Neuropeptide Hormone Activity Protein Binding Receptor Ligand Activity Peptide Hormone Receptor Binding	Metalloendopeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding Metallodipeptidase Activity
	Biological Process	Neuron Migration Signal Transduction Axonogenesis Digestion Cholecystokinin Signaling Pathway Eating Behavior	Proteolysis Epidermal Growth Factor Receptor Ligand Maturation Signaling Receptor Ligand Precursor Processing
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events
Drugs		Camostat
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 24348519 28448500 28892062) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (SNP x SNP interaction) ( 22344221) Body size at age 10 ( 32376654) Night sleep phenotypes ( 27126917)
Interacting Genes		7 interacting genes: CCKAR CCKBR CPE ENPEP MEP1A MEP1B UBQLN2	18 interacting genes: AGT CCK FN1 GCG GNRH1 GRP KNG1 LAMA1 LAMA5 MEP1B NPY NTS PLG POMC PTH SCT TAC1 VIP
Entrez ID		885	4224
HPRD ID		00321	02666
Ensembl ID		ENSG00000187094	ENSG00000112818
Uniprot IDs		P06307 Q6FG82	B7ZL91 Q16819
PDB IDs		7EZH 7EZK 7EZM 7MBX 7MBY 7XOU 8IA7 9BKJ 9BKK	7UAB 7UAC 7UAE 7UAF 7UAI
Enriched GO Terms of Interacting Partners?		Cholecystokinin Receptor Activity Metallopeptidase Activity Meprin A Complex Cholecystokinin Signaling Pathway Peptide Hormone Processing Signaling Receptor Ligand Precursor Processing Peptidase Activity Regulation Of Hormone Levels Proteolysis Protein Processing Hormone Metabolic Process Plasma Membrane Peptide Hormone Binding Protein Maturation Peptide Metabolic Process Type B Gastrin/cholecystokinin Receptor Binding Gastrin Receptor Activity Glutamyl Aminopeptidase Activity Metalloendopeptidase Activity Neuropeptide Signaling Pathway Epidermal Growth Factor Receptor Ligand Maturation Negative Regulation Of G Protein-coupled Receptor Internalization Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Protein Localization To Secretory Granule Regulation Of Biological Quality Membrane Extracellular Space Negative Regulation Of Clathrin-dependent Endocytosis Hydrolase Activity Protein Metabolic Process 1-phosphatidylinositol-3-kinase Regulator Activity G Protein-coupled Receptor Signaling Pathway PH Reduction Gastric Acid Secretion Metallodipeptidase Activity Insulin Processing Cytoplasmic Vesicle Zinc Ion Binding Cardiac Left Ventricle Morphogenesis Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Angiotensin Maturation Neurexin Family Protein Binding Glomerulus Development Negative Regulation Of Receptor Internalization Insulin Metabolic Process Peptide Catabolic Process Positive Regulation Of ERAD Pathway Regulation Of Clathrin-dependent Endocytosis Neuropeptide Receptor Activity G Protein-coupled Receptor Activity	Hormone Activity Extracellular Space Extracellular Region Receptor Ligand Activity Signaling Receptor Binding G Protein-coupled Receptor Signaling Pathway Neuropeptide Hormone Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Positive Regulation Of Cell Communication Positive Regulation Of Signaling Signal Transduction Neuropeptide Signaling Pathway Positive Regulation Of Signal Transduction Peptide Hormone Receptor Binding Antifungal Humoral Response Humoral Immune Response Regulation Of Hormone Secretion Regulation Of Signaling Regulation Of Multicellular Organismal Process Response To Yeast Regulation Of Hormone Levels Negative Regulation Of Multicellular Organismal Process Regulation Of Secretion By Cell Regulation Of Biological Quality Cell-cell Signaling Regulation Of Secretion Signaling Regulation Of Appetite Cell Communication Regulation Of Cell Communication Extracellular Matrix Blood Microparticle Killing Of Cells Of Another Organism Regulation Of Cell Adhesion Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Hormone Secretion Regulation Of Cell Population Proliferation Regulation Of Corticosterone Secretion Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Defense Response To Fungus Response To External Biotic Stimulus Regulation Of Blood Pressure Response To Hormone Defense Response Regulation Of Cell Migration Response To Fungus Antibacterial Humoral Response Cell Killing Platelet Alpha Granule Lumen
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?