CBR3 and S100A10

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		CBR3	S100A10
Description		carbonyl reductase 3	S100 calcium binding protein A10
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GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Cytoplasm Cytosol	Extracellular Region Cytoplasm Plasma Membrane Cell Surface Nuclear Matrix Extracellular Matrix Membrane Raft Extracellular Exosome RNA Polymerase II Transcription Regulator Complex Plasma Membrane Protein Complex AnxA2-p11 Complex
	Molecular Function	3-beta-hydroxysteroid 3-dehydrogenase (NADP+) Activity Carbonyl Reductase (NADPH) Activity Protein Binding NADPH Dehydrogenase (quinone) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor NADPH Binding	Calcium Ion Binding Protein Binding Lipid Binding Protein Homodimerization Activity Transmembrane Transporter Binding Calcium-dependent Protein Binding
	Biological Process	Xenobiotic Metabolic Process Phylloquinone Catabolic Process Cognition	Membrane Raft Assembly Vesicle Budding From Membrane Positive Regulation Of Plasminogen Activation MRNA Transcription By RNA Polymerase II Positive Regulation Of GTPase Activity Positive Regulation Of Exocytosis Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Neurogenesis Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Protein Localization To Plasma Membrane Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Plasma Membrane Repair
Pathways		Phase I - Functionalization of compounds	Dissolution of Fibrin Clot
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Blood protein levels ( 30072576) Lumbar spine bone mineral density ( 22504420)	Asthma ( 31619474) Diverticular disease ( 30177863) Serum metabolite levels ( 33031748) Urinary metabolite levels in chronic kidney disease ( 29545352) Urinary metabolite ratios in chronic kidney disease ( 29545352)
Interacting Genes		17 interacting genes: ANK1 ARIH2 ATP5PO BICD2 CLU IL10RB ITSN1 KCNE1 KCNJ15 PCP4 RAB35 RANBP9 RCAN1 S100A10 SDCBP SHOX2 UBC	23 interacting genes: ANXA2 ANXA7 BAD CBR3 CDK16 COPS6 CTSB DSCAM ERBB3 FSHR KCNK3 MLKL NANOS2 PLA2G4C PLG S100A3 S100Z SETDB1 SUMO2 TRPV5 TRPV6 USP2 ZGPAT
Entrez ID		874	6281
HPRD ID		07222	00232
Ensembl ID		ENSG00000159231	ENSG00000197747
Uniprot IDs		O75828 V9HW40	P60903
PDB IDs		2HRB	1A4P 1BT6 4DRW 4FTG 4HRE 4HRG 4HRH
Enriched GO Terms of Interacting Partners?		Cytoskeletal Anchor Activity Plasma Membrane Apical Dendrite	Calcium-dependent Protein Binding Calcium-dependent Phospholipid Binding Plasma Membrane S100 Protein Binding
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