SERPINB7 and RELCH

		SERPINB7	RELCH
Description		serpin family B member 7	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Endosome Golgi Apparatus Trans-Golgi Network Recycling Endosome
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Peptidase Inhibitor Activity
	Biological Process	Positive Regulation Of Transforming Growth Factor Beta1 Production Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Glomerular Mesangial Cell Proliferation Positive Regulation Of Platelet-derived Growth Factor Production	Lipid Transport Intracellular Cholesterol Transport
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Asthma ( 30929738 31361310 31619474 32296059 34103634) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 30929738 31036433) Asthma onset (childhood vs adult) ( 30929738) Food allergy ( 29051540) Hen's egg allergy ( 29051540) Systolic blood pressure ( 29208002)
Interacting Genes		10 interacting genes: FBXO22 HRH4 OGDH PHLPP1 PIGN RELCH RNF152 SLC5A2 TAX1BP1 ZCCHC2	3 interacting genes: SERPINB7 UBC ZCCHC2
Entrez ID		8710	57614
HPRD ID		04524	13866
Ensembl ID		ENSG00000166396	ENSG00000134444
Uniprot IDs		A8K3Q8 O75635	A0A2R8Y566 Q96ES0 Q9P260
PDB IDs
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Platelet-derived Growth Factor Production Regulation Of Platelet-derived Growth Factor Production Protein Tag Activity Positive Regulation Of Glomerular Mesangial Cell Proliferation Positive Regulation Of Transforming Growth Factor Beta1 Production Positive Regulation Of Cell Proliferation Involved In Kidney Development Regulation Of Glomerular Mesangial Cell Proliferation Positive Regulation Of Transforming Growth Factor Beta Production Positive Regulation Of Collagen Biosynthetic Process Regulation Of Collagen Biosynthetic Process Regulation Of Collagen Metabolic Process
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