KRT36 and KRT85

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRT36	KRT85
Description		keratin 36	keratin 85
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	Extracellular Space Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization Regulation Of Keratinocyte Differentiation	Epidermis Development Keratinization Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs
Diseases			Ectodermal dysplasia, pure hair-nail type (HNED)
GWAS			Body mass index ( 28552196)
Interacting Genes		60 interacting genes: ABI2 ABI3 AIMP2 AMOT APP BCAS2 C1orf216 CCBE1 CCHCR1 CDC23 DMRT3 EXOC8 GEM GPS2 HCK HGS HOXC8 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT73 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 MAP3K1 MYOZ1 MYOZ3 PKN1 PLEKHN1 PPP1R18 PSMB1 QARS1 RESF1 RIBC1 SMURF1 TMSB4X TRAF4 TSGA10IP TTC23 TTLL10 TXLNA ZNF414 ZNF785	27 interacting genes: ALOX12 CLIC3 CREB5 CYSRT1 GNE HAPLN2 KLHL38 KRT13 KRT14 KRT15 KRT16 KRT19 KRT25 KRT26 KRT27 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT39 KRT40 LHX8 OTX1 TAB2 ZNF655
Entrez ID		8689	3891
HPRD ID		05174	04139
Ensembl ID		ENSG00000126337	ENSG00000135443
Uniprot IDs		O76013	B7Z7N3 F5GYI5 P78386
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Keratinization Intermediate Filament Organization Keratin Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Cytosol Protein Binding Extracellular Exosome Epidermis Development Intermediate Filament Cytoskeleton Cornified Envelope FATZ Binding Tissue Development Telethonin Binding Actin-based Cell Projection Structural Constituent Of Cytoskeleton Aminoacyl-tRNA Synthetase Multienzyme Complex SCAR Complex Developmental Process Regulation Of Anatomical Structure Morphogenesis Peptidyl-tyrosine Phosphorylation	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Supramolecular Fiber Organization Cytoskeleton Organization Anatomical Structure Morphogenesis Cytoskeleton Extracellular Exosome Epidermis Development Cell Differentiation Hair Cycle Cellular Developmental Process Developmental Process Organelle Organization Structural Constituent Of Cytoskeleton Establishment Of Skin Barrier Skin Epidermis Development Cytosol Tissue Development Cornified Envelope Hair Follicle Morphogenesis Hepoxilin-epoxide Hydrolase Activity Lipoxin B4 Biosynthetic Process Protein Binding Diencephalon Morphogenesis N-acetylglucosamine Biosynthetic Process UDP-N-acetylglucosamine 2-epimerase Activity Leukotriene A4 Metabolic Process Lipoxin B4 Metabolic Process Linoleate 13S-lipoxygenase Activity Arachidonate 15-lipoxygenase Activity Lipoxin A4 Biosynthetic Process Intermediate Filament Cytoskeleton Protein-disulfide Reductase (glutathione) Activity N-acylmannosamine Kinase Activity N-acetylneuraminate Biosynthetic Process Lipoxin Biosynthetic Process Lipoxin A4 Metabolic Process Arachidonate 12(S)-lipoxygenase Activity Keratinocyte Differentiation Terminal Web Metencephalon Development Establishment Of Blood-nerve Barrier
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