EIF3C and EIF3K

Number of citations of the paper that reports this interaction (PubMedID 14519125)
0

Data Source:
HPRD (in vitro)

		EIF3C	EIF3K
Description		eukaryotic translation initiation factor 3 subunit C	eukaryotic translation initiation factor 3 subunit K
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GO Annotations	Cellular Component	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex	Nucleus Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Initiation Factor Binding Ribosome Binding	RNA Binding Translation Initiation Factor Activity Protein Binding Ribosome Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Cytoplasmic Translational Initiation Translation Translational Initiation Positive Regulation Of Translation	Formation Of Cytoplasmic Translation Initiation Complex Cytoplasmic Translational Initiation Translation Translational Initiation Regulation Of Translational Initiation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Crohn's disease ( 21102463 28067908) Extremely high intelligence ( 29520040) Inflammatory bowel disease ( 23128233 28067908) Inflammatory bowel disease (early onset) ( 19915574) Lamb consumption ( 32066663)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		26 interacting genes: AAGAB ALKBH4 BCKDK BTG3 CALM1 COXFA4L2 DOC2A DSCAM EIF1AX EIF3E EIF3G EIF3J EIF3K ERCC6 HMOX2 MAPK6 PFDN1 PLEKHF2 RNF10 RPS6KA3 SMAD9 SNCA SNIP1 TACC3 TAOK2 TRAPPC2	7 interacting genes: CCND3 EIF3C EIF3G EIF3H EIF3J EIF3L SPP1
Entrez ID		8663	27335
HPRD ID		04889	11740
Ensembl ID		ENSG00000184110	ENSG00000178982
Uniprot IDs		Q99613	K7EK53 K7ERF1 Q9UBQ5 U3LUI4
PDB IDs		3J8B 3J8C 6YBD 6YBW 6ZMW 6ZON 6ZP4 7A09 7QP6 7QP7 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPL 8RG0 8XXN 9BLN	1RZ4 3J8B 3J8C 6FEC 6YBD 6ZMW 6ZON 6ZP4 6ZVJ 7A09 7QP6 7QP7 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPL 8RG0 8XXN 9BLN
Enriched GO Terms of Interacting Partners?		Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Formation Of Cytoplasmic Translation Initiation Complex Eukaryotic Translation Initiation Factor 3 Complex Translation Initiation Factor Activity Translational Initiation Cytoplasmic Translational Initiation Protein-RNA Complex Assembly Regulation Of Acyl-CoA Biosynthetic Process Translation Vesicle-mediated Transport In Synapse Positive Regulation Of Vesicle Fusion	Formation Of Cytoplasmic Translation Initiation Complex Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 48S Preinitiation Complex Eukaryotic 43S Preinitiation Complex Cytoplasmic Translational Initiation Translation Initiation Factor Activity Translational Initiation Protein-RNA Complex Assembly Translation Viral Translational Termination-reinitiation Protein-containing Complex Assembly Protein-containing Complex Organization Macromolecule Biosynthetic Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Cyclin D3-CDK6 Complex Cyclin D3-CDK4 Complex Positive Regulation Of Estradiol Secretion Cellular Component Assembly Regulation Of Estradiol Secretion Viral Process RNA Binding Androgen Catabolic Process Protein Metabolic Process Cellular Response To Testosterone Stimulus Eukaryotic Translation Initiation Factor 3 Complex, EIF3m Response To 2,3,7,8-tetrachlorodibenzodioxine Response To Macrophage Colony-stimulating Factor Cyclin-dependent Protein Serine/threonine Kinase Activator Activity Cytosol Positive Regulation Of Bone Resorption Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Negative Regulation Of Neuron Projection Regeneration Metal-dependent Deubiquitinase Activity Hormone Catabolic Process
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