USO1 and SCFD1

Number of citations of the paper that reports this interaction (PubMedID 11927603)
55

Data Source:
BioGRID (biochemical, affinity chromatography technology, pull down)

		USO1	SCFD1
Description		USO1 vesicle transport factor	sec1 family domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Fibrillar Center Cytoplasm Endoplasmic Reticulum Golgi Apparatus Golgi Stack Microtubule Organizing Center Cytosol ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle Perinuclear Region Of Cytoplasm	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Golgi-associated Vesicle Cis-Golgi Network Cytosol Membrane Golgi Cisterna Membrane
	Molecular Function	RNA Binding Protein Binding Cadherin Binding	Protein Binding Syntaxin Binding Protein-containing Complex Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Small GTPase-mediated Signal Transduction Protein Transport Vesicle-mediated Transport Secretory Granule Localization Transcytosis Golgi Vesicle Transport Golgi Vesicle Docking Vesicle Fusion With Golgi Apparatus Membrane Fusion Regulation Of Cellular Response To Insulin Stimulus	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Post-Golgi Vesicle-mediated Transport Response To Toxic Substance Protein Transport Vesicle-mediated Transport Regulation Of Protein Transport Regulation Of ER To Golgi Vesicle-mediated Transport Negative Regulation Of Autophagosome Assembly
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport	COPII-mediated vesicle transport RHOA GTPase cycle
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Subjective response to lithium treatment in bipolar disorder ( 26503763)	Amyotrophic lateral sclerosis ( 27455348 29566793) Cognitive decline (age-related) ( 28078323) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		36 interacting genes: AKAP9 B4GALT2 BET1L BYSL C1orf94 CASP3 CASP8 CSNK2B DUSP12 EEA1 G3BP2 GABPB1 GAK GBF1 GOLGA2 GOLGB1 GOSR1 GOSR2 HLF LENG1 MORF4L1 NSF PHYKPL PLCG1 PRPF6 RAB1A RNF10 RPL9 SCFD1 SF1 SNW1 STX5 STXBP1 UTP14A XPO7 YKT6	6 interacting genes: DLST HECTD1 PPBP STX5 USO1 USP22
Entrez ID		8615	23256
HPRD ID		09135	10210
Ensembl ID		ENSG00000138768	ENSG00000092108
Uniprot IDs		O60763	A0A7I2V590 B7Z5N7 B7Z738 H0YIZ7 Q8WVM8
PDB IDs		2W3C
Enriched GO Terms of Interacting Partners?		Golgi Vesicle Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cis-Golgi Network Golgi Stack SNAP Receptor Activity Membrane Fusion Intracellular Transport Golgi Membrane SNARE Complex Golgi Organization Golgi Disassembly Golgi Apparatus Cytosolic Transport Vesicle-mediated Transport Cellular Localization Protein Transport Establishment Of Localization In Cell Retrograde Transport, Endosome To Golgi Syntaxin Binding Intracellular Protein Localization Establishment Of Protein Localization SNARE Binding Cytosol Endosomal Transport Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extrinsic Component Of Postsynaptic Density Membrane Vesicle Organization Intra-Golgi Vesicle-mediated Transport Vesicle Fusion Response To Anesthetic Post-Golgi Vesicle-mediated Transport Organelle Membrane Fusion Death-inducing Signaling Complex Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Positive Regulation Of Pyroptotic Inflammatory Response Organelle Fusion Response To Cobalt Ion Vesicle Docking Membrane Organization Organelle Organization Golgi Cisterna Membrane Death Receptor Binding Regulation Of Golgi Organization Organelle Localization By Membrane Tethering Organelle Disassembly Syntaxin-1 Binding Positive Regulation Of Glycoprotein Metabolic Process Intracellular Protein Transport Membrane Docking Execution Phase Of Apoptosis	Dihydrolipoyllysine-residue Succinyltransferase Activity ER To Golgi Transport Vesicle Membrane Vesicle Docking Organelle Localization By Membrane Tethering Membrane Docking Golgi Vesicle Docking Vesicle Fusion Organelle Membrane Fusion Golgi Organization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Organelle Fusion L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Oxoadipate Dehydrogenase Complex L-lysine Catabolic Process Membrane Fusion Histone H2B Deubiquitinase Activity Lysine Catabolic Process Oxoglutarate Dehydrogenase Complex Golgi Disassembly Positive Regulation Of Protein Catabolic Process Vesicle Fusion With Golgi Apparatus Histone H2A Deubiquitinase Activity Succinyl-CoA Metabolic Process D-glucose Transmembrane Transporter Activity Golgi Vesicle Transport Histone H4 Acetyltransferase Activity Amide Catabolic Process CXCR Chemokine Receptor Binding Vesicle Organization Cadherin Binding 2-oxoglutarate Metabolic Process Platelet Alpha Granule Early Endosome To Golgi Transport Regulation Of Golgi Organization Bounding Membrane Of Organelle Regulation Of Protein Catabolic Process Transcytosis Transcription Factor TFTC Complex
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