SLC25A12 and GPD2

Number of citations of the paper that reports this interaction (PubMedID 32877691)
0

Data Source:
BioGRID (proximity labelling technology)

		SLC25A12	GPD2
Description		solute carrier family 25 member 12	glycerol-3-phosphate dehydrogenase 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane	Mitochondrion Mitochondrial Inner Membrane
	Molecular Function	3-sulfino-L-alanine: Proton, Glutamate Antiporter Activity Aspartate:glutamate, Proton Antiporter Activity L-glutamate Transmembrane Transporter Activity Calcium Ion Binding Protein Binding Acidic Amino Acid Transmembrane Transporter Activity L-aspartate Transmembrane Transporter Activity Identical Protein Binding Metal Ion Binding	Glycerol-3-phosphate Dehydrogenase (quinone) Activity Calcium Ion Binding Oxidoreductase Activity Metal Ion Binding
	Biological Process	Neutral Amino Acid Transport Aspartate Transmembrane Transport L-glutamate Transmembrane Transport Malate-aspartate Shuttle Response To Calcium Ion Transmembrane Transport L-aspartate Transmembrane Transport Proton Transmembrane Transport	Glycerol-3-phosphate Metabolic Process Gluconeogenesis Glycerol-3-phosphate Shuttle Glycerol Catabolic Process NAD+ Metabolic Process Multicellular Organism Growth Camera-type Eye Development
Pathways		Mitochondrial protein import Aspartate and asparagine metabolism Malate-aspartate shuttle	Synthesis of PA Triglyceride catabolism
Drugs		Aspartic acid
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Refractive error ( 32231278)	Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Depression ( 29700475) Diisocyanate-induced asthma ( 25918132) Familial squamous cell lung carcinoma ( 29924316) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Motion sickness ( 25628336) Myopia ( 27182965) Possible neuropathic pain in post total joint replacement surgery for osteoarthritis ( 28051079) Refractive error ( 32231278) Response to statin therapy ( 20339536) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Ulcerative colitis ( 25082827) Urinary albumin-to-creatinine ratio ( 31630189)
Interacting Genes		1 interacting genes: JUND	1 interacting genes: ALDOA
Entrez ID		8604	2820
HPRD ID		04719	00715
Ensembl ID		ENSG00000115840	ENSG00000115159
Uniprot IDs		O75746	P43304 Q53T76
PDB IDs		4P5X 4P60
Enriched GO Terms of Interacting Partners?		Glycerol Catabolic Process Glycerol-3-phosphate Metabolic Process Glycerol-3-phosphate Shuttle Glycerol-3-phosphate Dehydrogenase (quinone) Activity Transcription Factor AP-1 Complex Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Glycerol Metabolic Process Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Response To Forskolin Osteoblast Development Positive Regulation Of Macrophage Activation
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