SLC25A12

Description		solute carrier family 25 member 12
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	3-sulfino-L-alanine: Proton, Glutamate Antiporter Activity Aspartate:glutamate, Proton Antiporter Activity L-glutamate Transmembrane Transporter Activity Calcium Ion Binding Protein Binding Acidic Amino Acid Transmembrane Transporter Activity L-aspartate Transmembrane Transporter Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Neutral Amino Acid Transport Aspartate Transmembrane Transport L-glutamate Transmembrane Transport Malate-aspartate Shuttle Response To Calcium Ion Transmembrane Transport L-aspartate Transmembrane Transport Proton Transmembrane Transport
Pathways		Mitochondrial protein import Aspartate and asparagine metabolism Malate-aspartate shuttle
Drugs		Aspartic acid
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Refractive error ( 32231278)
Novel Interacting Genes		2 novel interacting genes: GPD2 JUND
Interacting Genes		2 interacting genes: GPD2 JUND
Entrez ID		8604
HPRD ID		04719
Ensembl ID		ENSG00000115840
Uniprot IDs		O75746
PDB IDs		4P5X 4P60
Enriched GO Terms of Interacting Partners?		Glycerol Catabolic Process Glycerol-3-phosphate Metabolic Process Glycerol-3-phosphate Shuttle Glycerol-3-phosphate Dehydrogenase (quinone) Activity Transcription Factor AP-1 Complex Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Glycerol Metabolic Process Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Response To Forskolin Osteoblast Development Positive Regulation Of Macrophage Activation
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