CDC14A and KIF20A

Number of citations of the paper that reports this interaction (PubMedID 15263015)
30

Data Source:
BioGRID (pull down, two hybrid)

		CDC14A	KIF20A
Description		cell division cycle 14A	kinesin family member 20A
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Centrosome Microtubule Organizing Center Spindle Cytosol Cytoskeleton Stereocilium Stereocilium Tip Cell Projection Kinocilium Mitotic Spindle Kinociliary Basal Body	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Spindle Cytoskeleton Kinesin Complex Microtubule Midbody Cleavage Furrow Intercellular Bridge Mitotic Spindle
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity Protein Kinase Binding
	Biological Process	Microtubule Cytoskeleton Organization Regulation Of Exit From Mitosis Sensory Perception Of Sound Positive Regulation Of Cytokinesis Cell Division Cilium Assembly	Mitotic Cytokinesis Microtubule Bundle Formation Microtubule-based Movement Protein Transport Regulation Of Cytokinesis Midbody Abscission
Pathways		Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase MAPK6/MAPK4 signaling	MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Mitotic Telophase/Cytokinesis Kinesins
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462 31152163) Fasting glucose ( 34059833) Fever and diarrhea in mesalamine-treated irritable bowel disease ( 33501934) Systolic blood pressure x educational attainment (some college) interaction (2df) ( 32372009)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		16 interacting genes: AATK ATPAF2 BRAP C14orf119 CDC25B CDC6 CHRM1 FZR1 KIF20A LMTK2 PLK1 POLR2A PTK7 ROR2 TP53 WEE1	11 interacting genes: ATOSB CDC14A LRRK1 PCDHA9 RAB6A RAB6B RBFOX2 RYBP TFIP11 WEE2-AS1 ZRANB2
Entrez ID		8556	10112
HPRD ID		04614	09292
Ensembl ID		ENSG00000079335	ENSG00000112984
Uniprot IDs		A0A0U1RQX7 B4DY86 Q59EF4 Q9UNH5	O95235
PDB IDs			6YIP
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Cycle G2/M Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Signaling Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cytokinesis Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Process Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Process Protein Kinase Activity ATP Binding Negative Regulation Of Cell Cycle Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity G2/M Transition Of Mitotic Cell Cycle Mitotic G2/M Transition Checkpoint Regulation Of Cell Division Cell Cycle G2/M Phase Transition Regulation Of Cell Cycle Anaphase-promoting Complex Binding Mitotic DNA Damage Checkpoint Signaling Cell Division Mitotic Nuclear Membrane Disassembly Positive Regulation Of Ubiquitin-protein Transferase Activity Nuclear Membrane Disassembly Positive Regulation Of Mitotic Cell Cycle Phase Transition Membrane Disassembly DNA Damage Checkpoint Signaling Positive Regulation Of Cell Cycle Phase Transition Regulation Of DNA Replication Kinase Activity Positive Regulation Of Mitotic Cell Cycle Protein Tyrosine Kinase Activity Negative Regulation Of DNA Replication Negative Regulation Of DNA Metabolic Process Spindle Midzone Regulation Of Ubiquitin-protein Transferase Activity Mitotic Cell Cycle Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Signal Transduction In Response To DNA Damage Spindle Pole Positive Regulation Of Cell Cycle G2/M Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition	Protein Localization To Golgi Membrane Myosin V Binding Protein Localization To Golgi Apparatus Intra-Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Peptidyl-cysteine Methylation Retrograde Transport, Endosome To Golgi GTP Binding Endosome To Plasma Membrane Transport Vesicle Kinociliary Basal Body RNA Splicing Spliceosomal Complex Disassembly U2-type Post-mRNA Release Spliceosomal Complex
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