ALG10 and SERP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ALG10	SERP2
Description		ALG10 alpha-1,2-glucosyltransferase	stress associated endoplasmic reticulum protein family member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Transferase Activity Glycosyltransferase Activity Dolichyl Pyrophosphate Glc2Man9GlcNAc2 Alpha-1,2-glucosyltransferase Activity	Protein Binding
	Biological Process	Protein Glycosylation Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process	Response To Unfolded Protein Endoplasmic Reticulum Unfolded Protein Response
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
Drugs
Diseases
GWAS		Chronotype ( 30696823) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise ( 29769521) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Methadone dose in opioid dependence ( 28115739) Morning person ( 30696823) Triglyceride levels ( 32203549)	Chronic obstructive pulmonary disease ( 30804561) Dupuytren's disease ( 28886342) Fasting insulin (dietary factor interaction) ( 24204828) Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828)
Interacting Genes		8 interacting genes: CD79A ERGIC3 FBLN1 HERPUD2 KCNH1 KCNH2 SERP2 SHISAL1	54 interacting genes: ALG10 AQP6 BIK BSCL2 CERS4 CISD2 CKB CYB561 CYBRD1 EBP ELOVL4 ERGIC3 EWSR1 FAM210B FCGR2A FFAR2 FNDC9 FRMD3 GET1 GKN1 GPR152 GPR42 HSD17B13 KASH5 LHFPL5 LMNA LYVE1 MTIF3 MUC1 NEMP1 OPRM1 PTGES RETREG3 RNASEK SCN3B SLC10A6 SLC30A4 SLC38A1 SLC38A7 SLC71A2 SPACA1 STOM STX1A TIMMDC1 TM4SF18 TM4SF19 TMED8 TMEM106C TMEM14B TMEM179B TMEM237 TMEM31 TMEM80 TMX2
Entrez ID		84920	387923
HPRD ID		10346	16590
Ensembl ID		ENSG00000139133	ENSG00000151778
Uniprot IDs		Q5BKT4	Q8N6R1
PDB IDs
Enriched GO Terms of Interacting Partners?		Delayed Rectifier Potassium Channel Activity Negative Regulation Of Transformation Of Host Cell By Virus Voltage-gated Potassium Channel Activity Cyclic Nucleotide Binding Potassium Channel Activity Voltage-gated Potassium Channel Complex Regulation Of Heart Rate By Hormone Retrograde Transporter Complex, Golgi To ER Endoplasmic Reticulum Unfolded Protein Response Response To Unfolded Protein IgM B Cell Receptor Complex Regulation Of Transformation Of Host Cell By Virus Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate Monoatomic Ion Channel Complex B Cell Receptor Complex Transporter Complex Elastic Fiber Potassium Ion Transmembrane Transport Regulation Of Heart Rate By Chemical Signal Inward Rectifier Potassium Channel Complex Monoatomic Ion Channel Activity Potassium Ion Transport Negative Regulation Of Potassium Ion Export Across Plasma Membrane Fibrinogen Binding	Membrane Protein Binding Ascorbate Homeostasis Transmembrane Monodehydroascorbate Reductase Activity Endoplasmic Reticulum Membrane Endoplasmic Reticulum Glutamine Transport L-glutamine Transmembrane Transporter Activity
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