GEMIN2 and NUFIP1

Number of citations of the paper that reports this interaction (PubMedID 26275778)
67

Data Source:
BioGRID (pull down)

		GEMIN2	NUFIP1
Description		gem nuclear organelle associated protein 2	nuclear FMR1 interacting protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies	Fibrillar Center Nucleus Nucleoplasm Perichromatin Fibrils Nucleolus Transcription Elongation Factor Complex Nuclear Matrix Protein-containing Complex Synapse Presynaptic Active Zone Pre-snoRNP Complex
	Molecular Function	Protein Binding	DNA Binding RNA Binding Protein Binding Zinc Ion Binding SnoRNA Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Metal Ion Binding ATPase Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Protein-containing Complex Assembly	Box C/D SnoRNP Assembly RNA Processing Positive Regulation Of Transcription By RNA Polymerase II
Pathways		snRNP Assembly SARS-CoV-2 modulates host translation machinery
Drugs
Diseases
GWAS		Vitamin D levels ( 28757204)	Body mass index ( 25760438) HDL cholesterol levels ( 32203549) Oleic acid (18:1n-9) levels ( 23362303) Refractive error ( 32231278) Rosacea symptom severity ( 29771307)
Interacting Genes		34 interacting genes: AKAP6 BEND7 DDX20 DHX9 FBXO7 GEMIN5 HOXD10 IKBKG INCA1 KPNA6 MEOX1 MTNR1A NUFIP1 PAX6 PSMB1 RN7SL1 RNU1-1 RNU2-1 RPP14 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPN SPG21 SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2	12 interacting genes: BRCA1 CCNT1 DDX20 FMR1 GEMIN2 GEMIN4 GEMIN6 KLF6 OGT SNU13 TAF9 TTC3
Entrez ID		8487	26747
HPRD ID		03999	05073
Ensembl ID		ENSG00000092208	ENSG00000083635
Uniprot IDs		A0A8J9FJK1 A0A8J9FN78 O14893	Q9UHK0
PDB IDs		2LEH 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU	5L85
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing SMN-Sm Protein Complex Protein-RNA Complex Assembly RNA Splicing, Via Transesterification Reactions RNA Processing MRNA Metabolic Process Spliceosomal SnRNP Assembly RNA Metabolic Process MRNA Splicing, Via Spliceosome U1 SnRNP Spliceosomal Complex Assembly RNA Binding U2 SnRNP SMN Complex U4 SnRNP Nucleoplasm Nucleic Acid Metabolic Process Gemini Of Cajal Bodies Regulation Of MRNA Processing Small Nuclear Ribonucleoprotein Complex Protein-containing Complex Assembly Spliceosomal Complex U5 SnRNP Commitment Complex Regulation Of MRNA Splicing, Via Spliceosome PICln-Sm Protein Complex Protein-containing Complex Organization Nucleobase-containing Compound Metabolic Process 7-methylguanosine Cap Hypermethylation MRNA Binding Catalytic Step 2 Spliceosome U4/U6 X U5 Tri-snRNP Complex Regulation Of RNA Splicing Methylosome Sequence-specific MRNA Binding Regulation Of MRNA Metabolic Process Nucleus U2-type Prespliceosome Nuclear Body DNA-templated Transcription Termination Precatalytic Spliceosome Ribonucleoprotein Complex Regulation Of Alternative MRNA Splicing, Via Spliceosome Tertiary Granule Nucleic Acid Binding Cellular Response To Cytokine Stimulus U2-type Prespliceosome Assembly U12-type Spliceosomal Complex Cytoplasmic Ribonucleoprotein Granule	SMN Complex Gemini Of Cajal Bodies SMN-Sm Protein Complex Protein-RNA Complex Assembly Spliceosomal SnRNP Assembly Nucleoplasm MRNA Metabolic Process RNA Splicing MRNA Processing Nucleic Acid Metabolic Process RNA Metabolic Process Nucleolus Nuclear Body Nucleobase-containing Compound Metabolic Process Protein-containing Complex Assembly Nucleus Macromolecule Metabolic Process RNA Processing Protein-containing Complex Organization Box C/D SnoRNP Assembly Cellular Component Assembly RNA Polymerase Binding DNA-binding Transcription Factor Binding Regulation Of Lipid Biosynthetic Process Regulation Of Proteasomal Protein Catabolic Process RNA Splicing, Via Transesterification Reactions Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Spliceosomal Complex Assembly Molecular Condensate Scaffold Activity Transcription Cis-regulatory Region Binding Positive Regulation Of Intracellular Transport Of Viral Material Box C/D Sno(s)RNA Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Cajal Body Positive Regulation Of Transcription By RNA Polymerase II P53 Binding Regulation Of Lipid Metabolic Process Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex Host-mediated Perturbation Of Viral Process P-TEFb Complex Dendritic Filopodium Histone H3 Reader Activity U4atac SnRNP Dense Fibrillar Component
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