NFKBID and SS18

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		NFKBID	SS18
Description		NFKB inhibitor delta	SS18 subunit of BAF chromatin remodeling complex
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm Microtubule Cytoskeleton SWI/SNF Complex NpBAF Complex GBAF Complex
	Molecular Function	Protein Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Inflammatory Response Regulation Of Gene Expression T Cell Receptor Signaling Pathway Positive Regulation Of T-helper 17 Cell Differentiation	Microtubule Cytoskeleton Organization Cell Morphogenesis Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Response To Xenobiotic Stimulus Intracellular Signal Transduction Negative Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Ephrin Receptor Signaling Pathway Neuronal Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance
Pathways			Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Formation of the canonical BAF (cBAF) complex Formation of the embryonic stem cell BAF (esBAF) complex Formation of the non-canonical BAF (ncBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Diseases			Synovial sarcoma
GWAS			Autoimmune thyroid disease ( 32581359) Daytime nap ( 33568662) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Mean corpuscular hemoglobin ( 32888494) Nickel levels ( 26025379) Obesity-related traits ( 23251661) Periodontitis (Mean PAL) ( 24024966) QT interval (sulfonylurea treatment interaction) ( 27958378) Rhegmatogenous retinal detachment ( 23585552) Systemic juvenile idiopathic arthritis ( 27927641) Toenail selenium levels ( 25343990)
Interacting Genes		111 interacting genes: ADAMTSL4 AIRIM ANXA11 ARHGEF2 BEX2 C1orf94 CCHCR1 CRYBA2 CTRC CYB5R2 DDX25 DMRT3 DTX3 EFHC2 ELOA ESR2 FAAP20 FAM107A FARS2 FOXI1 GADD45GIP1 GFAP GIGYF1 GLYCTK GPANK1 GRB10 HDAC4 HNRNPF HNRNPH1 HOXA1 HOXB5 HOXC8 HOXC9 HOXD3 HSBP1L1 IHO1 IKZF3 INCA1 IRX6 KICS2 KRT19 KRT34 KRT40 KRT75 KRT76 KRTAP6-2 LCK LGALS14 LHX3 LMO2 LMO3 LMO4 MEOX2 MRPL28 MRPL53 MYEF2 NCK2 NDUFB7 NICN1 NUP54 PATL1 PATZ1 PAX6 PKP1 PLEKHN1 POMC POU4F2 PRDM6 PRMT7 PSMB8 PTCD1 QARS1 RAD51D RBM14 RBM41 RBM4B RFX2 RING1 RSPH1 RTP5 RUNX1 SAMD11 SAMD4A SCNM1 SH2D1B SH3RF1 SLU7 SMAD4 SMG9 SNAPC3 SORBS3 SPMIP2 SS18 SSC4D TCF19 TCF4 TCL1A TEKT4 TEKT5 TFIP11 TRAF2 TRIM29 TRIM9 TRIML2 TSEN54 TSSK3 UTP23 VIM ZBTB16 ZC2HC1B ZIC1	9 interacting genes: EP300 FUS GRB2 H3-3A MLLT10 NFKBID RBM14 SMARCA2 SMARCA4
Entrez ID		84807	6760
HPRD ID		18140	02559
Ensembl ID		ENSG00000167604	ENSG00000141380
Uniprot IDs		A0A286YF31 A0AAQ5BIF9 Q8NI38	B4DLD3 B4DR34 Q15532 Q4VAX0
PDB IDs			7VRB
Enriched GO Terms of Interacting Partners?		Protein Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II Intermediate Filament Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Nucleus RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of RNA Metabolic Process Intermediate Filament Regulation Of Transcription By RNA Polymerase II Cell Differentiation DNA-binding Transcription Factor Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Structural Constituent Of Skin Epidermis Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Cellular Developmental Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Anterior/posterior Pattern Specification Chromatin Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Speck Neuron Fate Specification Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Pattern Specification Process Regionalization RNA Metabolic Process Sequence-specific Double-stranded DNA Binding Positive Regulation Of Biosynthetic Process Developmental Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cell Fate Specification Positive Regulation Of Macromolecule Metabolic Process Ventral Spinal Cord Interneuron Specification MRNA Splicing, Via Spliceosome Supramolecular Fiber Organization Keratin Filament CD27 Signaling Pathway Embryonic Morphogenesis RNA Splicing, Via Transesterification Reactions Axonemal A Tubule Inner Sheath RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding	Epigenetic Regulation Of Gene Expression Transcription Coactivator Activity Positive Regulation Of T Cell Activation Positive Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of T Cell Differentiation Positive Regulation Of Lymphocyte Activation Positive Regulation Of Cell-cell Adhesion Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Lymphocyte Differentiation Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Leukocyte Differentiation Positive Regulation Of Cell Adhesion Transcription Initiation-coupled Chromatin Remodeling Regulation Of T Cell Differentiation Chromatin Binding Regulation Of Cell-cell Adhesion Nucleosome Array Spacer Activity Regulation Of Lymphocyte Activation Positive Regulation Of Immune System Process Regulation Of Lymphocyte Differentiation Regulation Of Organelle Organization Regulation Of Cell Activation Chromatin Remodeling BBAF Complex Positive Regulation Of Double-strand Break Repair Positive Regulation Of T-helper 17 Cell Differentiation NpBAF Complex GBAF Complex Regulation Of Cell Adhesion Chromatin Organization NBAF Complex Host-mediated Activation Of Viral Transcription Regulation Of Immune System Process Activation Of Immune Response Positive Regulation Of T-helper 17 Type Immune Response Regulation Of Hemopoiesis Positive Regulation Of DNA Repair Heterochromatin Formation Positive Regulation Of Cell Development Regulation Of Double-strand Break Repair Nucleoplasm Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Histone Binding Nuclear Androgen Receptor Binding Positive Regulation Of T-helper Cell Differentiation
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