SPATA22 and FAM107A

Number of citations of the paper that reports this interaction (PubMedID 28604741)
0

Data Source:
BioGRID (two hybrid)

		SPATA22	FAM107A
Description		spermatogenesis associated 22	family with sequence similarity 107 member A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome	Stress Fiber Nucleus Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Actin Cytoskeleton Membrane Nuclear Speck Ruffle Membrane Cell Projection Neuron Projection Synapse Anchoring Junction
	Molecular Function	Protein Binding	Actin Binding Protein Binding
	Biological Process	Meiotic DNA Repair Synthesis Homologous Chromosome Pairing At Meiosis Gamete Generation Fertilization Spermatocyte Division Meiotic Cell Cycle Regulation Of Meiotic Cell Cycle Reproductive System Development	Regulation Of Cell Growth Actin Filament Polymerization Positive Regulation Of Cell Migration Positive Regulation Of Protein Ubiquitination Regulation Of Protein Stability Cellular Response To Nutrient Levels Regulation Of Actin Cytoskeleton Organization Cognition Actin Filament Bundle Assembly Negative Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Cellular Response To Glucocorticoid Stimulus Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Caudal middle frontal gyrus volume ( 31530798)	Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917)
Interacting Genes		7 interacting genes: ECT2 FAM107A GOLGA2 HSF2BP KDM1A PRMT6 VHL	59 interacting genes: AGMAT APPBP2 AUH AZI2 BEGAIN BIRC8 CALCOCO2 CANX CCDC125 CCDC136 CCDC57 CCDC85B CPSF3 DAPK1 EFEMP2 EFHC2 EIF4A1 ESRRG FKBP6 FSD2 GFM2 GOLGA6L9 HFM1 HOOK2 HSF2BP HSPA14 HSPD1 HTRA1 IQUB ITPRID2 KRT15 KRT19 KRT27 KRT40 KRTAP4-12 LDOC1 LZTS2 MEIOB MID2 MTREX MTUS2 NEXN NFKBID NINL PLSCR1 PNMA1 POMP PSMD6 RAB18 RINT1 RNLS SPATA22 TADA2A TRAF2 TRIM37 TWF2 USHBP1 VIM WDR47
Entrez ID		84690	11170
HPRD ID		14862	09753
Ensembl ID		ENSG00000141255	ENSG00000168309
Uniprot IDs		A0A140VJV9 B4DHW8 F5GWB9 Q8NHS9	O95990 Q6IAM1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Modification Process Regulation Of Protein Modification Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Cytokinesis, Actomyosin Contractile Ring Assembly Cellular Response To Ionizing Radiation Negative Regulation Of Catabolic Process Histone H2AR3 Methyltransferase Activity Negative Regulation Of Autophagy Positive Regulation Of Protein Ubiquitination Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Histone H3R2 Methyltransferase Activity Centralspindlin Complex Positive Regulation Of Post-translational Protein Modification Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Histone Arginine N-methyltransferase Activity Mitotic Spindle Response To Ionizing Radiation Positive Regulation Of Mitotic Cytokinetic Process Protein Homooligomerization Regulation Of Primary Metabolic Process Cellular Response To Radiation Cellular Response To Stress Cell Morphogenesis Regulation Of Cell Differentiation Positive Regulation Of Protein Glycosylation Regulation Of Protein Glycosylation Golgi Disassembly DNA-binding Transcription Factor Binding Female Meiosis I Regulation Of Protein Ubiquitination Response To Fungicide MRF Binding Guanine Metabolic Process Protein Demethylase Activity Protein-arginine Omega-N Monomethyltransferase Activity Histone H4R3 Methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Positive Regulation Of Macromolecule Metabolic Process Transcription Elongation Factor Activity Histone H3K4 Demethylase Activity Positive Regulation Of Cell Differentiation Golgi Ribbon Formation Importin-alpha Family Protein Binding Double-strand Break Repair Involved In Meiotic Recombination Regulation Of Post-translational Protein Modification Histone H3K9 Demethylase Activity Protein-arginine N-methyltransferase Activity	Cytoskeleton Intermediate Filament Organization Intermediate Filament Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Microtubule Structural Constituent Of Skin Epidermis Meiosis I Cell Cycle Process Female Meiosis I Supramolecular Fiber Organization
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