PGBD1 and ZSCAN32

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		PGBD1	ZSCAN32
Description		piggyBac transposable element derived 1	zinc finger and SCAN domain containing 32
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Nucleus
	Molecular Function	DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Hemoglobin levels ( 32327693) Kawasaki disease ( 33106546) Lung cancer ( 28604730) Myopia ( 27182965) Pulse pressure ( 30578418) Refractive error ( 32231278) Squamous cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		8 interacting genes: MEOX2 NR4A1 TRAF2 ZKSCAN7 ZNF496 ZSCAN12 ZSCAN22 ZSCAN32	17 interacting genes: KEAP1 MAD1L1 NTAQ1 PGBD1 PHF1 SCAND1 TRAF2 TXN2 ZKSCAN4 ZKSCAN7 ZNF24 ZNF396 ZNF446 ZSCAN12 ZSCAN16 ZSCAN22 ZSCAN29
Entrez ID		84547	54925
HPRD ID		11426	15791
Ensembl ID		ENSG00000137338	ENSG00000140987
Uniprot IDs		Q96JS3	Q9NX65
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Zinc Ion Binding Regulation Of RNA Metabolic Process DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Sequence-specific Double-stranded DNA Binding Regulation Of Macromolecule Metabolic Process Metal Ion Binding Regulation Of Metabolic Process TORC2 Complex Disassembly TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Sphingolipid Binding IRE1-TRAF2-ASK1 Complex Tumor Necrosis Factor Receptor Superfamily Complex Detection Of Lipopolysaccharide Cellular Response To Corticotropin-releasing Hormone Stimulus Somite Specification CD27 Signaling Pathway Non-canonical Inflammasome Complex Assembly Tumor Necrosis Factor Binding Tumor Necrosis Factor Receptor Superfamily Binding	Zinc Ion Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA Binding Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Metabolic Process Identical Protein Binding Metal Ion Binding Nucleus Sequence-specific Double-stranded DNA Binding TORC2 Complex Disassembly Sequence-specific DNA Binding MAD1 Complex Protein-N-terminal Glutamine Amidohydrolase Activity TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Mitotic Spindle Assembly Checkpoint MAD1-MAD2 Complex Protein-N-terminal Asparagine Amidohydrolase Activity
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