DOC2B and DYNLT1

Number of citations of the paper that reports this interaction (PubMedID 9804756)
0

Data Source:
HPRD (in vitro, in vivo)

		DOC2B	DYNLT1
Description		double C2 domain beta	dynein light chain Tctex-type 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane SNARE Complex Synapse Presynapse	Extracellular Region Cytoplasm Golgi Apparatus Spindle Cytoskeleton Cytoplasmic Dynein Complex Microtubule Cytoplasmic Microtubule Dynein Complex Secretory Granule Lumen Host Cell Secretory Vesicle Ficolin-1-rich Granule Lumen
	Molecular Function	Calcium Ion Binding Calcium-dependent Phospholipid Binding Syntaxin Binding Metal Ion Binding	Protein Binding Identical Protein Binding Dynein Intermediate Chain Binding
	Biological Process	Chemical Synaptic Transmission Intracellular Protein Localization Positive Regulation Of Vesicle Fusion Positive Regulation Of Insulin Secretion Positive Regulation Of Calcium Ion-dependent Exocytosis Calcium Ion-regulated Exocytosis Of Neurotransmitter Spontaneous Neurotransmitter Secretion Calcium-dependent Activation Of Synaptic Vesicle Fusion	Establishment Of Mitotic Spindle Orientation Microtubule-based Movement Nervous System Development Regulation Of G Protein-coupled Receptor Signaling Pathway Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Intracellular Transport Symbiont Entry Into Host Cell Negative Regulation Of Neurogenesis Cell Division Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Transport Of Viral Material Towards Nucleus
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: DYNLT1 STXBP1 UNC13B	55 interacting genes: ACAT2 ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 CRHBP DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 ERO1A FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PRKN PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RPS6KA2 RRAGA SDCBP SIRPA SVIL SYNJ2 TCEANC TMEM143 TROAP TUBA3C TXN UXT VDAC1 XRN2
Entrez ID		8447	6993
HPRD ID		05196	15987
Ensembl ID		ENSG00000272636	ENSG00000146425
Uniprot IDs		Q14184	P63172
PDB IDs			5JPW 8J07 8PR0 8PR1 8PTK 8RGI
Enriched GO Terms of Interacting Partners?		Dense Core Granule Exocytosis Neuronal Dense Core Vesicle Exocytosis Regulation Of Synaptic Vesicle Priming Secretory Granule Localization Establishment Of Organelle Localization Syntaxin-1 Binding Synaptic Vesicle Priming Calcium-ion Regulated Exocytosis Vesicle Docking Involved In Exocytosis Organelle Localization Vesicle Docking Organelle Localization By Membrane Tethering Membrane Docking Positive Regulation Of Transport Regulated Exocytosis Establishment Of Vesicle Localization Vesicle Localization Positive Regulation Of Vesicle Docking Transport Of Viral Material Towards Nucleus Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Positive Regulation Of Synaptic Vesicle Priming Intracellular Transport Of Viral Protein In Host Cell Dense Core Granule Priming Exocytosis Axon Target Recognition Regulation Of Acrosomal Vesicle Exocytosis Extrinsic Component Of Presynaptic Membrane Presynaptic Dense Core Vesicle Exocytosis Positive Regulation Of Glutamate Secretion, Neurotransmission Negative Regulation Of Synaptic Transmission, GABAergic Establishment Of Localization In Cell Regulation Of Transport Platelet Degranulation Regulation Of Glutamate Secretion, Neurotransmission Positive Regulation Of Secretion By Cell Acrosomal Vesicle Exocytosis Chemical Synaptic Transmission Positive Regulation Of Secretion Positive Regulation Of Inhibitory Postsynaptic Potential Trans-synaptic Signaling Synaptic Signaling Modulation Of Inhibitory Postsynaptic Potential Synaptic Vesicle Maturation Intracellular Transport Of Virus Secretion By Cell Calcium Ion-regulated Exocytosis Of Neurotransmitter Host Cell Secretory Vesicle Regulation Of Protein-containing Complex Assembly Positive Regulation Of Glutamate Secretion	Aggresome Chemical Synaptic Transmission Frizzled Binding Trans-synaptic Signaling Synaptic Signaling Synapse PTB Domain Binding Convergent Extension Involved In Neural Plate Elongation Microtubule-based Process Outflow Tract Morphogenesis Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cytoplasm Presynapse Regulation Of JNK Cascade Amyloid Fibril Formation Convergent Extension Involved In Organogenesis Regulation Of Spontaneous Synaptic Transmission Spindle Pole Convergent Extension Involved In Gastrulation Aggresome Assembly Spontaneous Neurotransmitter Secretion Synaptic Vesicle Exocytosis Positive Regulation Of Cellular Component Organization Transport Along Microtubule Vesicle-mediated Transport In Synapse Dynein Light Chain Binding Neurotransmitter Transport Positive Regulation Of Neuron Projection Arborization Neurotransmitter Secretion Protein-folding Chaperone Binding Cellular Response To Manganese Ion Regulated Exocytosis Regulation Of Exocytosis Centriolar Subdistal Appendage Inclusion Body Assembly Cytoskeleton-dependent Intracellular Transport Negative Regulation Of Transport Apoptotic Process Hsp70 Protein Binding Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Type 2 Mitophagy Cell-cell Signaling Microtubule-based Transport Programmed Cell Death Cell Death Microtubule Convergent Extension Calcium-dependent Activation Of Synaptic Vesicle Fusion Microtubule Motor Activity Response To Manganese Ion
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