HOOK3 and IDO2

		HOOK3	IDO2
Description		hook microtubule tethering protein 3	indoleamine 2,3-dioxygenase 2
Image			No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Cytoplasm Golgi Apparatus Cis-Golgi Network Centrosome Cytoskeleton Microtubule HOPS Complex Centriolar Satellite FHF Complex	Cytoplasm Cytosol
	Molecular Function	Protein Binding Microtubule Binding Dynactin Binding Identical Protein Binding Dynein Light Chain Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding	Tryptophan 2,3-dioxygenase Activity Protein Binding Oxidoreductase Activity Heme Binding Indoleamine 2,3-dioxygenase Activity Metal Ion Binding Dioxygenase Activity
	Biological Process	Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Interkinetic Nuclear Migration Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Microtubule Anchoring At Centrosome Early Endosome To Late Endosome Transport Negative Regulation Of Neurogenesis Golgi Localization Protein Localization To Centrosome Neuronal Stem Cell Population Maintenance Protein Localization To Perinuclear Region Of Cytoplasm	Immune System Process L-tryptophan Catabolic Process L-tryptophan Catabolic Process To Kynurenine 'de Novo' NAD+ Biosynthetic Process From L-tryptophan
Pathways			Tryptophan catabolism
Drugs
Diseases
GWAS		Zinc levels ( 26025379)	Schizophrenia x sex interaction ( 34099189)
Interacting Genes		13 interacting genes: AKTIP CTIF EIF4ENIF1 HOOK1 HOOK2 IDO2 KRT13 MAPT MEOX2 MORC3 PNMA5 VPS16 VPS41	7 interacting genes: BANP GINS4 GPAT4 HOOK3 LZTS1 NKX6-3 SMIM19
Entrez ID		84376	169355
HPRD ID		09699	14113
Ensembl ID		ENSG00000168172	ENSG00000188676
Uniprot IDs		Q86VS8	Q6ZQW0
PDB IDs		5J8E 6B9H 8QAT 9KNS 9KO8
Enriched GO Terms of Interacting Partners?		HOPS Complex Endosome To Lysosome Transport FHF Complex Lysosomal Transport Protein Localization To Perinuclear Region Of Cytoplasm Vacuolar Transport Early Endosome To Late Endosome Transport Vesicle Organization Vacuole Organization Intracellular Transport Cytoplasmic Microtubule Organization Lysosome Organization Microtubule Binding Endosome Organization Endosomal Transport Cellular Localization Establishment Of Localization In Cell Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion Protein Transport Organelle Organization Establishment Of Protein Localization Dynein Light Intermediate Chain Binding Supramolecular Fiber Organization Cytoskeleton-dependent Intracellular Transport Histone-dependent DNA Binding Tubulin Complex Microtubule Lateral Binding Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Microtubule Cytoskeleton Intracellular Protein Localization Vesicle-mediated Transport Neurofibrillary Tangle Assembly Clathrin-coated Vesicle Lysosomal HOPS Complex Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Vacuole Fusion, Non-autophagic Indoleamine 2,3-dioxygenase Activity Cytoplasmic Ribonucleoprotein Granule Microtubule Tryptophan 2,3-dioxygenase Activity Vesicle Fusion Actin Binding Organelle Membrane Fusion PML Body Vesicle Tethering Complex Regulation Of Translation Regulation Of Protein Metabolic Process Main Axon Negative Regulation Of Mitochondrial Fission
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?