TMEM101 and STX10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM101	STX10
Description		transmembrane protein 101	syntaxin 10
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Endomembrane System Membrane Synaptic Vesicle Membrane Organelle Membrane SNARE Complex Vesicle Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Positive Regulation Of Canonical NF-kappaB Signal Transduction	Intracellular Protein Transport Vesicle Fusion Protein Transport Vesicle-mediated Transport Regulation Of Protein Localization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Vesicle Docking
Pathways			Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823) Venous thromboembolism ( 31420334)
Interacting Genes		22 interacting genes: ACKR5 ARLN BNIP3 CCR4 DCAKD DRD2 GIMAP1 MAP4K1 NDUFA3 NINJ2 NPSR1 PDZK1IP1 PKMYT1 STRIT1 STX10 SYNJ2BP TMEM243 TMEM65 TMIE VAMP1 VAMP2 VAPB	6 interacting genes: COQ8A CXorf66 STX1A STX4 TMEM101 USP2-AS1
Entrez ID		84336	8677
HPRD ID		14623	04791
Ensembl ID		ENSG00000091947	ENSG00000104915
Uniprot IDs		B4DFS4 Q96IK0	O60499 Q5U8S2 X6R2W0
PDB IDs			4DND
Enriched GO Terms of Interacting Partners?		Membrane Synaptic Vesicle Membrane SNARE Complex SNAP Receptor Activity Syntaxin Binding Mitochondrial Outer Membrane SNARE Complex Assembly Interneuron Migration Vesicle Fusion Organelle Membrane Fusion Vesicle Organization Organelle Fusion	SNARE Complex Assembly SNARE Complex Positive Regulation Of Regulated Secretory Pathway SNAP Receptor Activity SNARE Binding Vesicle Docking Schaffer Collateral - CA1 Synapse Membrane Docking Neurotransmitter Transport Positive Regulation Of Exocytosis Vesicle Fusion Myosin Head/neck Binding Organelle Localization By Membrane Tethering Sphingomyelin Phosphodiesterase Activator Activity Organelle Membrane Fusion Positive Regulation Of Eosinophil Degranulation Storage Vacuole Positive Regulation Of Synaptic Transmission Organelle Fusion Positive Regulation Of Norepinephrine Secretion Regulation Of Regulated Secretory Pathway Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Neuron Projection Membrane Membrane Fusion Regulation Of Insulin Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Lateral Loop Regulation Of Exocytosis Regulation Of Peptide Hormone Secretion Exocytosis Cornified Envelope Assembly Myelin Sheath Adaxonal Region Extrinsic Component Of Mitochondrial Inner Membrane ATP-dependent Protein Binding Response To Gravity Chloride Channel Inhibitor Activity Actomyosin Regulation Of Hormone Secretion Regulation Of Protein Secretion Endomembrane System Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Regulation Of Norepinephrine Secretion Positive Regulation Of Catecholamine Secretion Positive Regulation Of Secretion By Cell Vesicle Organization Positive Regulation Of Secretion Calcium Channel Inhibitor Activity Specific Granule
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