WDR75 and MFSD6

		WDR75	MFSD6
Description		WD repeat domain 75	major facilitator superfamily domain containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Small-subunit Processome	Plasma Membrane Membrane
	Molecular Function	RNA Binding Protein Binding	Protein Binding
	Biological Process	RRNA Processing Ribosome Biogenesis Ribosomal Small Subunit Biogenesis Positive Regulation Of Transcription By RNA Polymerase I Positive Regulation Of RRNA Processing	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Iron status biomarkers (ferritin levels) ( 25352340) Iron status biomarkers (total iron binding capacity) ( 28334935) Iron status biomarkers (transferrin levels) ( 25352340) Iron status biomarkers (transferrin saturation) ( 28334935) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Arthritis (juvenile idiopathic) ( 33106285) Daytime sleep phenotypes ( 27126917) Estimated glomerular filtration rate ( 31015462) Medication use (thyroid preparations) ( 31015401) Platelet count ( 32888494)
Interacting Genes		3 interacting genes: MCPH1 MFSD6 RNF10	44 interacting genes: ADIPOQ AKAP19 ALG8 ANKAR APH1A APOL3 AQP7 C19orf18 CD79A CYB5R3 EBP ERGIC3 FAM209A GJA8 GJB2 GPR152 GPR42 GPX8 HIBCH LY6E MSTN NKG7 OSGEPL1 PDCD1LG2 SELENOK SGPL1 SHISAL1 SLC10A1 SLC10A6 SLC16A2 SLC18A1 SLC39A2 SLC60A2 SMIM1 SSMEM1 STAT1 STX12 SYNDIG1 TMEM179B TMEM237 TMEM242 TMEM258 TSPO2 WDR75
Entrez ID		84128	54842
HPRD ID		07775	13369
Ensembl ID		ENSG00000115368	ENSG00000151690
Uniprot IDs		Q8IWA0	B7Z7Y2 Q6ZSS7
PDB IDs		7MQ8 7MQ9 7MQA
Enriched GO Terms of Interacting Partners?			Membrane Organic Hydroxy Compound Transport Bile Acid:sodium Symporter Activity Gap Junction-mediated Intercellular Transport
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