WDR54 and NUDT22

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		WDR54	NUDT22
Description		WD repeat domain 54	nudix hydrolase 22
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Motile Cilium Vesicle	Nucleoplasm
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding UDP-sugar Diphosphatase Activity Hydrolase Activity Metal Ion Binding GDP-mannose Hydrolase Activity
	Biological Process	Negative Regulation Of Receptor Internalization Single Fertilization Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of MAPK Cascade
Pathways
Drugs
Diseases
GWAS		Stress urinary incontinence ( 31729902)	Crohn's disease ( 28067908) Fruit consumption ( 32066663)
Interacting Genes		3 interacting genes: NUDT22 RBPMS UBC	22 interacting genes: ARID5A DDIT4L DNAL4 IKZF5 INCA1 KLHL26 LHX3 RUSC1 SAXO1 TCF4 TLE5 USP54 WDR54 ZBTB33 ZMYND12 ZNF143 ZNF19 ZNF343 ZNF398 ZNF581 ZNF648 ZNF655
Entrez ID		84058	84304
HPRD ID		08577	14434
Ensembl ID		ENSG00000005448	ENSG00000149761
Uniprot IDs		Q9H977	Q9BRQ3
PDB IDs			5LF9 5LOR 5LOU 5R50 5R51 5R52 5R53 5R54 5R55 5R56 5R57 5R58 5R59 5R5A 5R5B 5R5C 5R5D 5R5E 5R5F 5R5G 5R5H 5R5I 5R5J 5R5K 5R5L 5R5M 5R5N 5R5O 5R5P 5R5Q 5R5R 5R5S 5RKZ
Enriched GO Terms of Interacting Partners?		GDP-mannose Hydrolase Activity UDP-sugar Diphosphatase Activity MRNA CDS Binding Protein Tag Activity Pre-mRNA Binding Pre-mRNA Intronic Binding	Regulation Of Transcription By RNA Polymerase II DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Zinc Ion Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process
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