L3MBTL2 and TUBGCP6

		L3MBTL2	TUBGCP6
Description		L3MBTL histone methyl-lysine binding protein 2	tubulin gamma complex component 6
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GO Annotations	Cellular Component	Nucleus Nucleoplasm	Spindle Pole Gamma-tubulin Complex Gamma-tubulin Ring Complex Cytoplasm Centrosome Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Membrane
	Molecular Function	Chromatin Binding Protein Binding Zinc Ion Binding Histone Binding Metal Ion Binding Histone H4K20me2 Reader Activity Histone H4K20me1 Reader Activity Promoter-specific Chromatin Binding	Microtubule Binding Gamma-tubulin Binding Microtubule Minus-end Binding
	Biological Process	Chromatin Organization Regulation Of DNA-templated Transcription Ectoderm Development Negative Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Stem Cell Differentiation Stem Cell Proliferation	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle
Pathways		SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety ( 33859377) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 26192919) Lamb consumption ( 32066663) Major depressive disorder ( 27479909) Neuroticism ( 27918536 29255261) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Acne (severe) ( 24927181) Major depressive disorder ( 27479909) Obesity-related traits ( 23251661)
Interacting Genes		53 interacting genes: AMOTL2 BEND7 BIVM CARD9 CCDC106 CCDC33 CEP76 CYB5R3 DRC4 EFHC2 EIF4ENIF1 FAM217B GKAP1 GOLGA2 GPRASP3 H3C1 H4C1 HSF2BP LNX2 MEAF6 MEOX1 MPP3 NRF1 PAICS PHF10 PIAS1 PICK1 POU6F2 PRKAR1B RBAK REL SSUH2 STAC3 STAM2 TAFA5 TAX1BP1 TBC1D9B TEKT1 THAP1 THAP11 TLE5 TNNI1 TRIM42 TRIM50 TSPYL1 TUBGCP6 XPNPEP3 ZBTB26 ZBTB48 ZFP64 ZFY ZNF467 ZNF829	3 interacting genes: CYB5R3 FNDC3B L3MBTL2
Entrez ID		83746	85378
HPRD ID		13954	15589
Ensembl ID		ENSG00000100395	ENSG00000128159
Uniprot IDs		A0A0S2Z5X6 Q969R5	Q96RT7
PDB IDs		2W0T 3CEY 3F70	6M33 6V6C 6V6S 6X0U 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 7QJE 8Q62 8RX1 8VRD 8VRJ 8VRK 9H9P
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding	Nitric-oxide Synthase Complex Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Nitrite Reductase (NO-forming) Activity Histone H4K20me1 Reader Activity Histone H4K20me2 Reader Activity Hemoglobin Complex Ectoderm Development Nitric Oxide Biosynthetic Process Sterol Biosynthetic Process Nitric Oxide Metabolic Process FAD Binding Reactive Nitrogen Species Metabolic Process Cholesterol Biosynthetic Process Blood Circulation
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