C11orf68 and EIF4H

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		C11orf68	EIF4H
Description		chromosome 11 open reading frame 68	eukaryotic translation initiation factor 4H
Image			No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Membrane Eukaryotic Translation Initiation Factor 4F Complex Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding	Nucleic Acid Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding RNA Strand Annealing Activity RNA Strand-exchange Activity Ribosomal Small Subunit Binding Cadherin Binding
	Biological Process		Formation Of Translation Preinitiation Complex Translation Translational Initiation Regulation Of Translational Initiation Sexual Reproduction Developmental Growth Eukaryotic Translation Initiation Factor 4F Complex Assembly
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Asthma ( 31959851)
Interacting Genes		14 interacting genes: CSDE1 EIF4H KCNE3 KLF15 MEOX2 MTCL1 NONO PHETA1 REL SDCBP SH3GL3 TRAPPC2L ZNF341 ZNF512B	13 interacting genes: C11orf68 CCL24 CEBPA DDIT4L DLG3 FBXO17 LAT2 LNX1 PICK1 PTPN12 RFC2 SPG21 STT3B
Entrez ID		83638	7458
HPRD ID		12553	11940
Ensembl ID		ENSG00000175573	ENSG00000106682
Uniprot IDs		Q9H3H3	Q15056
PDB IDs		1ZTP 2Q4K
Enriched GO Terms of Interacting Partners?
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