CANX and CD1D

Number of citations of the paper that reports this interaction (PubMedID 12239218)
0

Data Source:
HPRD (in vivo)

		CANX	CD1D
Description		calnexin	CD1d molecule
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Nuclear Membrane Mitochondrial Membrane Melanosome Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Endoplasmic Reticulum Quality Control Compartment Extracellular Exosome Lumenal Side Of Endoplasmic Reticulum Membrane Presynapse	Extracellular Space Cytoplasm Lysosome Lysosomal Membrane Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane External Side Of Plasma Membrane Cell Surface Endosome Membrane Membrane Basolateral Plasma Membrane
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding Carbohydrate Binding Metal Ion Binding Unfolded Protein Binding	Protein Binding Beta-2-microglobulin Binding Lipid Antigen Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Cell Adhesion Molecule Binding Lipopeptide Binding
	Biological Process	Protein Folding Protein Secretion Viral Protein Processing Protein Folding In Endoplasmic Reticulum ERAD Pathway Synaptic Vesicle Endocytosis Clathrin-dependent Endocytosis	Positive Regulation Of T Cell Mediated Cytotoxicity Immune System Process Immune Response Detection Of Bacterium Heterotypic Cell-cell Adhesion Positive Regulation Of T Cell Proliferation T Cell Selection Innate Immune Response Positive Regulation Of Innate Immune Response Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib
Pathways		Assembly of Viral Components at the Budding Site MHC class II antigen presentation Interleukin-35 Signalling Calnexin/calreticulin cycle Interleukin-27 signaling Maturation of spike protein Maturation of spike protein Regulation of CDH1 posttranslational processing and trafficking to plasma membrane Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Antihemophilic factor, human recombinant Tenecteplase Lanoteplase Calcium citrate Calcium Phosphate Lonoctocog alfa Moroctocog alfa Calcium phosphate dihydrate	cis-tetracosenoyl sulfatide
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Lymphocyte count ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494) Resting heart rate ( 24680774) White blood cell count ( 27863252 32888494)	Dental caries (decayed and filled deciduous teeth) ( 31533690)
Interacting Genes		48 interacting genes: ABCC2 APOB BCAP31 CD1D CD3D CD82 CFTR CSNK2A1 EBI3 EDEM1 F2RL1 F8 FAM107A FSHR GPR35 GRIA1 GRIN1 HLA-A HTR3A IFNGR1 ITGA6 ITGB1 LCT LHCGR LINC01554 LPA LRP1 LTB4R2 MBTPS1 MDM2 MTNR1A MTNR1B NDRG1 NUTF2 PDIA3 PLP1 PMP22 PRKCSH SERP1 SLC2A1 SLC4A1 SLC6A4 SMURF2 SUMO1 TF TG TRA TSHR	8 interacting genes: APOE B2M CALR CANX CD74 P4HB PTPRC TRB
Entrez ID		821	912
HPRD ID		00252	01780
Ensembl ID		ENSG00000127022	ENSG00000158473
Uniprot IDs		A0A7P0T937 A0A7P0TAE9 A0A7P0TB65 P27824	A0A669KAZ2 A0A669KB34 P15813
PDB IDs			1ZT4 2PO6 3HUJ 3SDX 3TZV 3U0P 3VWJ 3VWK 4EN3 4LHU 4MNG 4MQ7 4WO4 4WW2 4WWK 6V7Y 6V7Z 6V80 8SGB 8SGM 8SOS
Enriched GO Terms of Interacting Partners?		Plasma Membrane Membrane Signaling Receptor Activity Signal Transduction Cell Surface Protein-hormone Receptor Activity Regulation Of Transport Circulatory System Process G Protein-coupled Peptide Receptor Activity Regulation Of Biological Quality Recycling Endosome Membrane Vascular Process In Circulatory System G Protein-coupled Receptor Activity Integrin Alpha6-beta1 Complex Positive Regulation Of Transport G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Endoplasmic Reticulum Lumen T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Protein Localization To Nuclear Pore Positive Regulation Of Retrograde Protein Transport, ER To Cytosol Regulation Of Protein Transport Positive Regulation Of Protein Catabolic Process Positive Regulation Of Protein Localization Clathrin-coated Endocytic Vesicle Membrane Response To Stress Melatonin Receptor Activity Response To Endoplasmic Reticulum Stress Basolateral Plasma Membrane Positive Regulation Of Protein Transport Cell Activation Detection Of Biotic Stimulus Regulation Of Cellular Localization Ligand-gated Monoatomic Ion Channel Activity Regulation Of Establishment Of Protein Localization Conditioned Place Preference Regulation Of Ubiquitin-dependent Protein Catabolic Process System Process Endosome Membrane Alpha-beta T Cell Receptor Complex Associative Learning Immune Response To Tumor Cell Positive Regulation Of Metabolic Process Regulation Of Protein Localization Regulation Of Multicellular Organismal Process Beta-2-microglobulin Binding Bicarbonate Transmembrane Transporter Activity Regulation Of Membrane Potential Receptor Complex Ligand-gated Ion Channel Signaling Pathway Synapse	Protein Folding Protein Folding In Endoplasmic Reticulum Endoplasmic Reticulum Lumen External Side Of Plasma Membrane Lumenal Side Of Endoplasmic Reticulum Membrane Positive Regulation Of Endocytosis Positive Regulation Of Cell Adhesion Extracellular Exosome MHC Class I Peptide Loading Complex Regulation Of Endocytosis Peptide Antigen Assembly With MHC Class I Protein Complex Endoplasmic Reticulum Regulation Of Cell Adhesion Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Positive Thymic T Cell Selection Negative Thymic T Cell Selection Regulation Of Immune System Process Negative T Cell Selection Lymphocyte Mediated Immunity Positive T Cell Selection Positive Regulation Of Viral Entry Into Host Cell MHC Class II Protein Complex Focal Adhesion Heparan Sulfate Proteoglycan Binding Regulation Of Cell Migration Endocytic Vesicle Lumen T Cell Mediated Cytotoxicity Leukocyte Mediated Immunity Regulation Of Cell Motility Positive Regulation Of Immune System Process Positive Regulation Of Leukocyte Migration Regulation Of Viral Entry Into Host Cell Thymic T Cell Selection Regulation Of Locomotion Response To Stress Protein Transport Endoplasmic Reticulum Quality Control Compartment Positive Regulation Of Viral Life Cycle MHC Class II Protein Complex Binding Regulation Of Vesicle-mediated Transport Negative Regulation Of Multicellular Organismal Process Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Cell Migration Antigen Processing And Presentation Of Endogenous Antigen T Cell Selection Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Production Of Molecular Mediator Of Immune Response Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
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