KRTAP1-3 and PRPF31

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP1-3	PRPF31
Description		keratin associated protein 1-3	pre-mRNA processing factor 31
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U4 SnRNP U4atac SnRNP Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome MLL1 Complex Spliceosomal Tri-snRNP Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	RNA Binding Protein Binding U4 SnRNA Binding U4atac SnRNA Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Ribonucleoprotein Complex Binding SnRNP Binding
	Biological Process		Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing SnoRNA Localization Ribonucleoprotein Complex Localization
Pathways		Keratinization	mRNA Splicing - Major Pathway
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS			Change in HbA1c levels in response to metformin treatment in type 2 diabetes ( 29650774)
Interacting Genes		183 interacting genes: ADAM12 AGA ALDH3B1 ALPP ATG9A BCAM BHLHE40 BMP7 BTC C19orf25 C2orf68 CATSPER1 CELF5 CHIC2 CHRD CHRNG CLDN2 CMTM8 CNNM3 COA5 COL8A1 CRCT1 CREB5 CRH CRY2 CTNNBIP1 CXCL16 CYP21A2 CYSRT1 DAGLB DHRS1 DLGAP3 DMRT3 DOCK2 ECE1 EMC7 FBXW5 FZD10 GLP1R GLRX3 GLYAT GNE GRAP2 GSTP1 HCK HHEX HHIPL1 HOXA1 HOXB9 HOXC8 HPCAL1 HSD3B7 IGSF8 IL10 IL16 INPP5D INS ITGB4 ITGB5 JOSD1 KLHL38 KLK8 KPRP KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LONRF1 LRFN4 MAPKBP1 MOS MTNR1A MXD3 MXI1 MYPOP NAXD NECTIN2 NECTIN3 NID2 NMU NPBWR2 NPDC1 NR1D2 NUFIP2 OLFM2 OTX1 P3H3 PDE9A PDIA5 PHETA1 PHLDA1 PIGS PLEKHN1 PRF1 PRKAA2 PRKAB2 PRPF31 PSMA1 PTK7 PTPMT1 PVR R3HDM2 RAMAC RANBP3 RASD1 RPN1 RPS19BP1 SAPCD2 SDC3 SDCBP SELENOM SHFL SLC13A5 SLC22A23 SLC23A1 SLC39A7 SLC43A2 SLC5A5 SLC7A11 SMCP SPINT1 SPRY1 STK16 SUSD6 TACSTD2 TCAF1 TFAP2D TGFB1 THAP7 TNS2 UNC119 UTP23 UXT VASN VSTM4 WNT11 XCL2 YIPF3 YY1 ZDHHC1 ZFTRAF1 ZNF330 ZNF414 ZNF417 ZNF440 ZNF446 ZNF497 ZNF587 ZNF696 ZNF764 ZNF786 ZNF837	140 interacting genes: APOBEC3C ASB15 BICD2 C1QTNF1 CALCOCO2 CAPNS2 CARD14 CBY2 CCDC106 CCDC136 CCDC33 CCDC57 CCDC70 CCNDBP1 CDC23 CDCA7L CDR2L CEBPA CEP70 CYSRT1 DVL2 DVL3 EFEMP2 EIF3E EVI5 EXOSC8 FANCA FANCC FASTK FLACC1 FSD2 FXR1 GOLGA2 GOLGA6L9 GPRASP3 HAP1 HES7 HNRNPH2 HNRNPK HOOK2 HSF2BP JAKMIP2 KANK2 KCTD6 KHDRBS2 KHDRBS3 KIFC3 KRT15 KRT31 KRT34 KRT35 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP19-5 KRTAP4-11 KRTAP6-3 LBX1 LDOC1 LHX8 LURAP1 LZTS2 MDFI MEIS3 MEOX2 MID2 MIPOL1 MKRN3 MTUS2 NCAPH2 NCKIPSD NDUFB9 NOTCH2NLA OGT PAK5 PDE4DIP PHC2 PHF5A PICK1 PLEKHG4 PNMA1 PNMA2 PNMA3 PPIH PPP1R16A PPP2R3C PRDM14 PRICKLE1 PRPF3 PSTPIP1 RACK1 RBAK RBM25 RBM4 RBMX RBMY1A1 RBMY1F RBMY1J REL RINT1 RUNDC3A SIAH1 SLAIN1 SNRNP200 SRSF3 SSX2IP STX11 TADA2A TFIP11 TLE5 TMCC2 TP53BP2 TRIM14 TRIM23 TRIM27 TRIM41 TSGA10 UBXN11 USH1G USP15 VWC2 ZFP64 ZFP69B ZNF24 ZNF250 ZNF408 ZNF417 ZNF473 ZNF48 ZNF587 ZNF668 ZNF71 ZNF774 ZNF792 ZNF837 ZSCAN22
Entrez ID		81850	26121
HPRD ID		12305	05917
Ensembl ID		ENSG00000221880	ENSG00000105618
Uniprot IDs		Q8IUG1	Q8WWY3
PDB IDs			2OZB 3JCR 3SIU 3SIV 5O9Z 6AH0 6AHD 6QW6 6QX9 8H6E 8H6J 8H6K 8H6L 8Q7N 8QO9 8QOZ 8QP8 8QP9 8QPA 8QPB 8QPE 8QPK 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5 8Y6O
Enriched GO Terms of Interacting Partners?		Epidermis Development Keratinization Protein Binding Intermediate Filament Keratin Filament Tissue Development Hair Cycle Susceptibility To T Cell Mediated Cytotoxicity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Animal Organ Morphogenesis Negative Regulation Of Defense Response Identical Protein Binding	Protein Binding Intermediate Filament Keratin Filament Identical Protein Binding Nucleus Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing Regulation Of MRNA Processing MRNA Processing Regulation Of RNA Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Metabolic Process Spliceosomal Complex Regulation Of Nucleobase-containing Compound Metabolic Process Structural Constituent Of Skin Epidermis RNA Splicing Nucleic Acid Binding Regulation Of MRNA Metabolic Process Zinc Ion Binding Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Primary Metabolic Process RNA Processing Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression MRNA Binding Negative Regulation Of Viral Transcription Cytoskeleton Intermediate Filament Organization Positive Regulation Of RNA Splicing Regulation Of RNA Biosynthetic Process Regulation Of Viral Transcription
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?