CLPB and TTF2

Number of citations of the paper that reports this interaction (PubMedID 12927788)
0

Data Source:
HPRD (two hybrid)

		CLPB	TTF2
Description		ClpB family mitochondrial disaggregase	transcription termination factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Intermembrane Space	Nucleus Spliceosomal Complex Cytoplasm Cytosol Transcription Elongation Factor Complex
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity ATP-dependent Protein Disaggregase Activity	Nucleotide Binding DNA Binding Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Granulocyte Differentiation Cellular Response To Heat RIG-I Signaling Pathway Antiviral Innate Immune Response	DNA Repair DNA-templated Transcription Termination Termination Of RNA Polymerase II Transcription MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heart rate response to recovery post exercise (10 sec) ( 29497042) Height ( 31562340) Platelet distribution width ( 32888494)
Interacting Genes		7 interacting genes: CEP70 MDFI NRIP1 OGT SMAD9 TTF2 WEE2-AS1	27 interacting genes: CDC5L CDKL3 CEBPA CLPB DCP1A DRAP1 FZR1 GMEB2 HINFP HNRNPA1 HNRNPA2B1 KIF4A LINC01554 MATR3 MYB MYBL2 NVL PDCD6IP PRDX4 SKIL SMAD1 SMAD7 TACC3 TCF4 TNIP1 UBC ZSCAN1
Entrez ID		81570	8458
HPRD ID		11560	05280
Ensembl ID		ENSG00000162129	ENSG00000116830
Uniprot IDs		A0A140VK11 Q9H078	Q9UNY4
PDB IDs		7TTR 7TTS 7US2 7XBK 7XC5 8DEH 8FDS
Enriched GO Terms of Interacting Partners?		Circadian Regulation Of Gene Expression Ovarian Follicle Rupture Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly	Nucleus Identical Protein Binding Nuclear Matrix DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process RNA Metabolic Process WD40-repeat Domain Binding DNA Binding Regulation Of Transcription By RNA Polymerase II Transcription Regulator Complex MiRNA Binding Regulation Of Macromolecule Metabolic Process Heteromeric SMAD Protein Complex G-rich Strand Telomeric DNA Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Regulation Of Cell Cycle Regulation Of Metabolic Process Primary MiRNA Processing Regulation Of Primary Metabolic Process Positive Regulation Of Telomere Maintenance Regulation Of RNA Metabolic Process Nucleoplasm Lens Fiber Cell Differentiation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process I-SMAD Binding Positive Regulation Of Cell Differentiation Catalytic Step 2 Spliceosome Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Response To Stress Regulation Of RNA Biosynthetic Process Protein Domain Specific Binding Mitotic Spindle Organization Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II DNA Damage Checkpoint Signaling DNA-templated Transcription Negative Regulation Of Cell Differentiation Regulation Of Chromosome Organization Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Leukemia Inhibitory Factor Blastocyst Formation Response To Leukemia Inhibitory Factor Positive Regulation Of Chromosome Organization Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Telomere Maintenance
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